Single breath-hold slice-following CSPAMM myocardial tagging

M. Stuber, M. A. Spiegel, S. E. Fischer, M. B. Scheidegger, P. G. Danias, E. M. Pedersen, P. Boesiger

Research output: Contribution to journalArticlepeer-review

74 Scopus citations


Myocardial tagging has shown to be a useful magnetic resonance modality for the assessment and quantification of local myocardial function. Many myocardial tagging techniques suffer from a rapid fading of the tags, restricting their application mainly to systolic phases of the cardiac cycle. However, left ventricular diastolic dysfunction has been increasingly appreciated as a major cause of heart failure. Subtraction based slice- following CSPAMM myocardial tagging has shown to overcome limitations such as fading of the tags. Remaining impediments to this technique, however, are extensive scanning times (~ 10 min), the requirement of repeated breath- holds using a coached breathing pattern, and the enhanced sensitivity to artifacts related to poor patient compliance or inconsistent depths of end- expiratory breath-holds. We therefore propose a combination of slice- following CSPAMM myocardial tagging with a segmented EPI imaging sequence. Together with an optimized RF excitation scheme, this enables to acquire as many as 20 systolic and diastolic grid-tagged images per cardiac cycle with a high tagging contrast during a short period of sustained respiration.

Original languageEnglish (US)
Pages (from-to)85-91
Number of pages7
JournalMagnetic Resonance Materials in Physics, Biology and Medicine
Issue number1-2
StatePublished - Oct 1999


  • Diastolic function
  • Myocardial motion analysis
  • Myocardial tagging
  • Slice following
  • Torsion

ASJC Scopus subject areas

  • Biophysics
  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging


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