Abstract
The hypothesis that components of the silicone breast implant potentiate antibody response is tested. The ability of silicone oil, silicone gel, and octamethylcyclotetrasiloxane [D4] to potentiate antibody production against a conventional test antigen bovine serum albumin (BSA) in mice is evaluated to determine the adjuvant effect of silicone products. Seventy A/J mice are used and tissue samples are analyzed by light microscopy and analysis of variance (ANOVA). Results showed that viscous silicone products potentiate antibody response. These silicone products can also exert a synergistic effect with other adjuvants.
| Original language | English (US) |
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| Number of pages | 1 |
| State | Published - Dec 1 1996 |
| Event | Proceedings of the 1996 5th World Biomaterials Congress. Part 2 (of 2) - Toronto, Can Duration: May 29 1996 → Jun 2 1996 |
Other
| Other | Proceedings of the 1996 5th World Biomaterials Congress. Part 2 (of 2) |
|---|---|
| City | Toronto, Can |
| Period | 5/29/96 → 6/2/96 |
ASJC Scopus subject areas
- General Materials Science