Signaling in the Immunological Synapse: Defining the Optimal Size

Abraham Kupfer

doi:10.1016/j.immuni.2006.07.005

Signaling in the Immunological Synapse: Defining the Optimal Size

Abraham Kupfer

School of Medicine

Research output: Contribution to journal › Short survey › peer-review

11 Scopus citations

Abstract

In this issue of Immunity, Varma et al. (2006) report that in the synapses between T cells and planar bilayers, T cell receptor (TCR) proximal signaling takes place in peripheral TCR-microclusters that form continually and that TCR signaling ceases when they fuse with the central supramolecular activation cluster.

Original language	English (US)
Pages (from-to)	11-13
Number of pages	3
Journal	Immunity
Volume	25
Issue number	1
DOIs	https://doi.org/10.1016/j.immuni.2006.07.005
State	Published - Jul 2006

ASJC Scopus subject areas

Immunology and Allergy
Immunology
Infectious Diseases

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10.1016/j.immuni.2006.07.005

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title = "Signaling in the Immunological Synapse: Defining the Optimal Size",

abstract = "In this issue of Immunity, Varma et al. (2006) report that in the synapses between T cells and planar bilayers, T cell receptor (TCR) proximal signaling takes place in peripheral TCR-microclusters that form continually and that TCR signaling ceases when they fuse with the central supramolecular activation cluster.",

author = "Abraham Kupfer",

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AB - In this issue of Immunity, Varma et al. (2006) report that in the synapses between T cells and planar bilayers, T cell receptor (TCR) proximal signaling takes place in peripheral TCR-microclusters that form continually and that TCR signaling ceases when they fuse with the central supramolecular activation cluster.

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Signaling in the Immunological Synapse: Defining the Optimal Size

Abstract

ASJC Scopus subject areas

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