Signaling in the Immunological Synapse: Defining the Optimal Size

Research output: Contribution to journalShort surveypeer-review

11 Scopus citations


In this issue of Immunity, Varma et al. (2006) report that in the synapses between T cells and planar bilayers, T cell receptor (TCR) proximal signaling takes place in peripheral TCR-microclusters that form continually and that TCR signaling ceases when they fuse with the central supramolecular activation cluster.

Original languageEnglish (US)
Pages (from-to)11-13
Number of pages3
Issue number1
StatePublished - Jul 2006

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Infectious Diseases


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