Sickle cell trait is not associated with an increased risk of heart failure or abnormalities of cardiac structure and function

Natalie A. Bello; Hyacinth I. Hyacinth; Nicholas S. Roetker; Samantha R. Seals; Rakhi P. Naik; Vimal K. Derebail; Abhijit V. Kshirsagar; Nigel S. Key; James G. Wilson; Adolfo Correa; Robert J. Adams; Leonard D. Egede; W. T. Longstreth; Gaurav Choudhary; Beatrice E. Gee; Austin L. Hughes; Amil M. Shah; Joann E. Manson; Matthew Allison; Gregory L. Burke; Aaron R. Folsom; Cara L. Carty; Alexander P. Reiner; Scott D. Solomon; Suma H. Konety

doi:10.1182/blood-2016-08-705541

Sickle cell trait is not associated with an increased risk of heart failure or abnormalities of cardiac structure and function

Natalie A. Bello, Hyacinth I. Hyacinth, Nicholas S. Roetker, Samantha R. Seals, Rakhi P. Naik, Vimal K. Derebail, Abhijit V. Kshirsagar, Nigel S. Key, James G. Wilson, Adolfo Correa, Robert J. Adams, Leonard D. Egede, W. T. Longstreth, Gaurav Choudhary, Beatrice E. Gee, Austin L. Hughes, Amil M. Shah, Joann E. Manson, Matthew Allison, Gregory L. BurkeAaron R. Folsom, Cara L. Carty, Alexander P. Reiner, Scott D. Solomon, Suma H. Konety

School of Medicine

Research output: Contribution to journal › Letter › peer-review

9 Scopus citations

Original language	English (US)
Pages (from-to)	799-801
Number of pages	3
Journal	Blood
Volume	129
Issue number	6
DOIs	https://doi.org/10.1182/blood-2016-08-705541
State	Published - Feb 9 2017

ASJC Scopus subject areas

Biochemistry
Immunology
Hematology
Cell Biology

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Bello, N. A., Hyacinth, H. I., Roetker, N. S., Seals, S. R., Naik, R. P., Derebail, V. K., Kshirsagar, A. V., Key, N. S., Wilson, J. G., Correa, A., Adams, R. J., Egede, L. D., Longstreth, W. T., Choudhary, G., Gee, B. E., Hughes, A. L., Shah, A. M., Manson, J. E., Allison, M., ... Konety, S. H. (2017). Sickle cell trait is not associated with an increased risk of heart failure or abnormalities of cardiac structure and function. Blood, 129(6), 799-801. https://doi.org/10.1182/blood-2016-08-705541

Bello, NA, Hyacinth, HI, Roetker, NS, Seals, SR, Naik, RP, Derebail, VK, Kshirsagar, AV, Key, NS, Wilson, JG, Correa, A, Adams, RJ, Egede, LD, Longstreth, WT, Choudhary, G, Gee, BE, Hughes, AL, Shah, AM, Manson, JE, Allison, M, Burke, GL, Folsom, AR, Carty, CL, Reiner, AP, Solomon, SD & Konety, SH 2017, 'Sickle cell trait is not associated with an increased risk of heart failure or abnormalities of cardiac structure and function', Blood, vol. 129, no. 6, pp. 799-801. https://doi.org/10.1182/blood-2016-08-705541

@article{fb9d58479bbb40fdbbf78c20bc96e82a,

title = "Sickle cell trait is not associated with an increased risk of heart failure or abnormalities of cardiac structure and function",

author = "Bello, {Natalie A.} and Hyacinth, {Hyacinth I.} and Roetker, {Nicholas S.} and Seals, {Samantha R.} and Naik, {Rakhi P.} and Derebail, {Vimal K.} and Kshirsagar, {Abhijit V.} and Key, {Nigel S.} and Wilson, {James G.} and Adolfo Correa and Adams, {Robert J.} and Egede, {Leonard D.} and Longstreth, {W. T.} and Gaurav Choudhary and Gee, {Beatrice E.} and Hughes, {Austin L.} and Shah, {Amil M.} and Manson, {Joann E.} and Matthew Allison and Burke, {Gregory L.} and Folsom, {Aaron R.} and Carty, {Cara L.} and Reiner, {Alexander P.} and Solomon, {Scott D.} and Konety, {Suma H.}",

note = "Funding Information: The authors thank the other investigators, staff, and participants of the Atherosclerosis Risk in Communities (ARIC) study, the Multi-Ethnic Study of Atherosclerosis (MESA) study, the Jackson Heart Study (JHS), and the Women's Health Initiative (WHI). The ARIC study is a collaborative study supported by the National Institutes of Health (NIH), National Heart, Lung, and Blood Institute (NHLBI) contracts (HHSN268201100005C, HHSN268201100006C, HHSN268201100007C, HHSN268201100008C, HHSN268201100009C, HHSN268201100010C, HHSN268201100011C, and HHSN268201100012C) and NIH/NHLBI grant 5K12 HL087097-0. MESA and the MESA SNP Health Association Resource (SHARe) projects are conducted and supported by the NIH/NHLBI in collaboration with MESA investigators; MESA is supported by grants from the NIH/NHLBI (HHSN268201500003I, N01-HC-95159, N01-HC-95160, N01-HC-95161, N01-HC-95162, N01-HC-95163, N01-HC-95164, N01-HC-95165, N01-HC-95166, N01-HC-95167, N01-HC-95168, N01-HC-95169, UL1-TR-001079, UL1-TR-000040) and NIH, National Institute of Diabetes and Digestive and Kidney Diseases (DK063491). The JHS is supported by grants from the NIH/NHLBI and the National Institute on Minority Health and Health Disparities (HHSN268201300046C, HHSN268201300047C, HHSN268201300048C, HHSN268201300049C, and HSN268201300050C). The WHI program is funded by the NIH, NIH/NHLBI, and US Department of Health and Human Services through contracts (HHSN268201100046C, HHSN268201100001C, HHSN268201100002C, HHSN268201100003C, HHSN268201100004C, and HHSN271201100004C). This work is supported by grants from NIH/NHLBI (3U01 HL117721 02S2) and an Emory Pediatrics pilot grant (00051285) (H.I.H.); NIH/NHLBI (UO1 HL117659) and the Doris Duke Charitable Foundation (2013123) (N.S.K.); and the NIH/NHLBI (1K08HL125100) (R.P.N.). Full lists of participating investigators and institutions can be found as follows: MESA (http://www.mesa-nhlbi.org), JHS (https://www.jacksonheartstudy.org/jhsinfo/Home/tabid/36/Default.aspx), and WHI (https://www.whi.org/SitePages/WHI%20Home.aspx).",

year = "2017",

month = feb,

day = "9",

doi = "10.1182/blood-2016-08-705541",

language = "English (US)",

volume = "129",

pages = "799--801",

journal = "Blood",

issn = "0006-4971",

publisher = "American Society of Hematology",

number = "6",

}

TY - JOUR

T1 - Sickle cell trait is not associated with an increased risk of heart failure or abnormalities of cardiac structure and function

AU - Bello, Natalie A.

AU - Hyacinth, Hyacinth I.

AU - Roetker, Nicholas S.

AU - Seals, Samantha R.

AU - Naik, Rakhi P.

AU - Derebail, Vimal K.

AU - Kshirsagar, Abhijit V.

AU - Key, Nigel S.

AU - Wilson, James G.

AU - Correa, Adolfo

AU - Adams, Robert J.

AU - Egede, Leonard D.

AU - Longstreth, W. T.

AU - Choudhary, Gaurav

AU - Gee, Beatrice E.

AU - Hughes, Austin L.

AU - Shah, Amil M.

AU - Manson, Joann E.

AU - Allison, Matthew

AU - Burke, Gregory L.

AU - Folsom, Aaron R.

AU - Carty, Cara L.

AU - Reiner, Alexander P.

AU - Solomon, Scott D.

AU - Konety, Suma H.

N1 - Funding Information: The authors thank the other investigators, staff, and participants of the Atherosclerosis Risk in Communities (ARIC) study, the Multi-Ethnic Study of Atherosclerosis (MESA) study, the Jackson Heart Study (JHS), and the Women's Health Initiative (WHI). The ARIC study is a collaborative study supported by the National Institutes of Health (NIH), National Heart, Lung, and Blood Institute (NHLBI) contracts (HHSN268201100005C, HHSN268201100006C, HHSN268201100007C, HHSN268201100008C, HHSN268201100009C, HHSN268201100010C, HHSN268201100011C, and HHSN268201100012C) and NIH/NHLBI grant 5K12 HL087097-0. MESA and the MESA SNP Health Association Resource (SHARe) projects are conducted and supported by the NIH/NHLBI in collaboration with MESA investigators; MESA is supported by grants from the NIH/NHLBI (HHSN268201500003I, N01-HC-95159, N01-HC-95160, N01-HC-95161, N01-HC-95162, N01-HC-95163, N01-HC-95164, N01-HC-95165, N01-HC-95166, N01-HC-95167, N01-HC-95168, N01-HC-95169, UL1-TR-001079, UL1-TR-000040) and NIH, National Institute of Diabetes and Digestive and Kidney Diseases (DK063491). The JHS is supported by grants from the NIH/NHLBI and the National Institute on Minority Health and Health Disparities (HHSN268201300046C, HHSN268201300047C, HHSN268201300048C, HHSN268201300049C, and HSN268201300050C). The WHI program is funded by the NIH, NIH/NHLBI, and US Department of Health and Human Services through contracts (HHSN268201100046C, HHSN268201100001C, HHSN268201100002C, HHSN268201100003C, HHSN268201100004C, and HHSN271201100004C). This work is supported by grants from NIH/NHLBI (3U01 HL117721 02S2) and an Emory Pediatrics pilot grant (00051285) (H.I.H.); NIH/NHLBI (UO1 HL117659) and the Doris Duke Charitable Foundation (2013123) (N.S.K.); and the NIH/NHLBI (1K08HL125100) (R.P.N.). Full lists of participating investigators and institutions can be found as follows: MESA (http://www.mesa-nhlbi.org), JHS (https://www.jacksonheartstudy.org/jhsinfo/Home/tabid/36/Default.aspx), and WHI (https://www.whi.org/SitePages/WHI%20Home.aspx).

PY - 2017/2/9

Y1 - 2017/2/9

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UR - http://www.scopus.com/inward/citedby.url?scp=85014815030&partnerID=8YFLogxK

U2 - 10.1182/blood-2016-08-705541

DO - 10.1182/blood-2016-08-705541

M3 - Letter

C2 - 27932373

AN - SCOPUS:85014815030

SN - 0006-4971

VL - 129

SP - 799

EP - 801

JO - Blood

JF - Blood

IS - 6

ER -

Sickle cell trait is not associated with an increased risk of heart failure or abnormalities of cardiac structure and function

ASJC Scopus subject areas

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