Sickle Cell Disease and Stroke: Diagnosis and Management

Courtney Lawrence, Jennifer Webb

Research output: Contribution to journalReview articlepeer-review

15 Scopus citations


Both adult and pediatric patients with sickle cell disease face a higher risk of stroke than the general population. Given the different underlying pathophysiology predisposing these patients to stroke, providers should be aware of differences in guidelines for stroke management. This paper reviews diagnostic considerations and recommendations during the evaluation and acute management of patients with sickle cell disease presenting with stroke, focusing on recent updates in the literature. Given the high recurrence rate of stroke in these patients, secondary prevention and curative measures will also be reviewed.

Original languageEnglish (US)
Article number27
Pages (from-to)1-10
Number of pages10
JournalCurrent neurology and neuroscience reports
Issue number3
StatePublished - Mar 1 2016
Externally publishedYes


  • CVA
  • Cerebrovascular accident
  • SCD
  • Sickle cell disease
  • Stroke

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Neurology


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