TY - JOUR
T1 - Short communication
T2 - Fracture risk by HIV infection status in perinatally HIV-exposed children
AU - Siberry, George K.
AU - Li, Hong
AU - Jacobson, Denise
PY - 2012/3/1
Y1 - 2012/3/1
N2 - The objective of this study was to examine the incidence of fractures in HIV-infected children and comparable HIV-exposed, uninfected (HEU) children in a multicenter, prospective cohort study (PACTG 219/219C) in the United States. The main outcome was first fracture during the risk period. Nine fractures occurred in 7 of 1326 HIV-infected and 2 of 649 HEU children, corresponding to incidence rates of 1.2 per 1000 person-years and 1.1 per 1000 person-years, respectively. The incidence rate ratio was 1.1 (95% CI 0.2, 5.5). There was no evidence of a substantially increased risk of fracture in HIV-infected compared to HEU children.
AB - The objective of this study was to examine the incidence of fractures in HIV-infected children and comparable HIV-exposed, uninfected (HEU) children in a multicenter, prospective cohort study (PACTG 219/219C) in the United States. The main outcome was first fracture during the risk period. Nine fractures occurred in 7 of 1326 HIV-infected and 2 of 649 HEU children, corresponding to incidence rates of 1.2 per 1000 person-years and 1.1 per 1000 person-years, respectively. The incidence rate ratio was 1.1 (95% CI 0.2, 5.5). There was no evidence of a substantially increased risk of fracture in HIV-infected compared to HEU children.
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U2 - 10.1089/aid.2011.0064
DO - 10.1089/aid.2011.0064
M3 - Article
C2 - 22471877
AN - SCOPUS:84858128507
SN - 0889-2229
VL - 28
SP - 247
EP - 250
JO - AIDS research and human retroviruses
JF - AIDS research and human retroviruses
IS - 3
ER -