Sex-related differences in epidemiological and clinic-based headache studies

E. Anne MacGregor, Jason D. Rosenberg, Tobias Kurth

Research output: Contribution to journalReview articlepeer-review

66 Scopus citations


This manuscript discusses sex-related differences in headache prevalence, the symptoms and natural history of migraine, associated disability, and co-morbid disorders. The role of sex hormones is discussed with reference to the effects of hormonal events across the reproductive years and the specific effects of the menstrual cycle on migraine. Differences between the sexes were identified across all parameters reviewed. Future research should ensure that data are analyzed separately for men and women to ensure that differences between the sexes are identified.

Original languageEnglish (US)
Pages (from-to)843-859
Number of pages17
Issue number6
StatePublished - Jun 1 2011


  • epidemiology
  • headache
  • hormone
  • migraine
  • sex

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology


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