TY - JOUR
T1 - Sex and gender impact immune responses to vaccines among the elderly
AU - Fink, Ashley L.
AU - Klein, Sabra L.
N1 - Publisher Copyright:
© 2015 Int. Union Physiol. Sci./Am. Physiol. Soc.
PY - 2015/11/1
Y1 - 2015/11/1
N2 - In response to the recommended vaccines in older-aged individuals, sex differences occur in response to those that protect against influenza, tetanus, pertussis, shingles, and pneumococcal infections. The efficacy of vaccines recommended for older-aged adults is consistently greater for females than for males. Gender differences as well as biological sex differences can influence vaccine uptake, responses, and outcome in older-aged individuals, which should influence guidelines, formulations, and dosage recommendations for vaccines in the elderly.
AB - In response to the recommended vaccines in older-aged individuals, sex differences occur in response to those that protect against influenza, tetanus, pertussis, shingles, and pneumococcal infections. The efficacy of vaccines recommended for older-aged adults is consistently greater for females than for males. Gender differences as well as biological sex differences can influence vaccine uptake, responses, and outcome in older-aged individuals, which should influence guidelines, formulations, and dosage recommendations for vaccines in the elderly.
UR - http://www.scopus.com/inward/record.url?scp=84946404697&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84946404697&partnerID=8YFLogxK
U2 - 10.1152/physiol.00035.2015
DO - 10.1152/physiol.00035.2015
M3 - Review article
C2 - 26525340
AN - SCOPUS:84946404697
SN - 1548-9213
VL - 30
SP - 408
EP - 416
JO - Physiology
JF - Physiology
IS - 6
ER -