Seroincidence of porcine T. solium infection in the Peruvian highlands

H. H. Garcia; A. E. Gonzalez; C. Gavidia; N. Falcon; T. Bernal; M. Verastegui; S. Rodriguez; V. C.W. Tsang; R. H. Gilman; H. Mayta; J. Jimenez; P. Castillo; C. A.W. Evans

doi:10.1016/S0167-5877(02)00234-9

Seroincidence of porcine T. solium infection in the Peruvian highlands

H. H. Garcia, A. E. Gonzalez, C. Gavidia, N. Falcon, T. Bernal, M. Verastegui, S. Rodriguez, V. C.W. Tsang, R. H. Gilman, H. Mayta, J. Jimenez, P. Castillo, C. A.W. Evans

Bloomberg School of Public Health

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

We performed repeated serological sampling of pigs in an endemic area of the Peruvian highlands (eight villages) to assess the feasibility of detecting incident cases of Taenia solium infection as indicators of ongoing transmission of the parasite. A total of 2245 samples corresponding to 1548 pigs were collected in three sampling rounds (n = 716, 926, and 603, respectively). Village-period specific seroprevalences of antibodies by enzyme-linked immunoelectrotransfer blot (EITB) assay varied from 39% (95% CI: 34, 44) to 76% (95% CI: 72, 79). The prevalence of cysticercosis increased with the age of the pigs (similarly for both sexes). Around 40% of pigs were re-sampled at the end of each 4-month period. Crude incidence risks were 48% (57/120, 95% CI: 43-52) and 58% (111/192, 95% CI: 54-61) for each period. A proportion of seropositive animals became seronegative at the end of each period (23 and 15%). Incidence varied by the village, and the exposure period, and was higher in males than females (but did not differ by age).

Original language	English (US)
Pages (from-to)	227-236
Number of pages	10
Journal	Preventive Veterinary Medicine
Volume	57
Issue number	4
DOIs	https://doi.org/10.1016/S0167-5877(02)00234-9
State	Published - Apr 15 2003

Keywords

Cysticercosis
EITB
Epidemiology
Incidence
Longitudinal studies
Taenia solium

ASJC Scopus subject areas

Food Animals
Animal Science and Zoology

Access to Document

10.1016/S0167-5877(02)00234-9

Cite this

@article{e825318e2a1f456fb2f881defe5a5a45,

title = "Seroincidence of porcine T. solium infection in the Peruvian highlands",

abstract = "We performed repeated serological sampling of pigs in an endemic area of the Peruvian highlands (eight villages) to assess the feasibility of detecting incident cases of Taenia solium infection as indicators of ongoing transmission of the parasite. A total of 2245 samples corresponding to 1548 pigs were collected in three sampling rounds (n = 716, 926, and 603, respectively). Village-period specific seroprevalences of antibodies by enzyme-linked immunoelectrotransfer blot (EITB) assay varied from 39% (95% CI: 34, 44) to 76% (95% CI: 72, 79). The prevalence of cysticercosis increased with the age of the pigs (similarly for both sexes). Around 40% of pigs were re-sampled at the end of each 4-month period. Crude incidence risks were 48% (57/120, 95% CI: 43-52) and 58% (111/192, 95% CI: 54-61) for each period. A proportion of seropositive animals became seronegative at the end of each period (23 and 15%). Incidence varied by the village, and the exposure period, and was higher in males than females (but did not differ by age).",

keywords = "Cysticercosis, EITB, Epidemiology, Incidence, Longitudinal studies, Taenia solium",

author = "Garcia, {H. H.} and Gonzalez, {A. E.} and C. Gavidia and N. Falcon and T. Bernal and M. Verastegui and S. Rodriguez and Tsang, {V. C.W.} and Gilman, {R. H.} and H. Mayta and J. Jimenez and P. Castillo and Evans, {C. A.W.}",

note = "Funding Information: We are indebted to the people of the Mantaro Valley, who allowed us to do this study. Help from Dr. L.H. Moulton and from M.T. Lopez, C. Guezala, P. Rodriguez, E. Perez, A. Ramirez and C. Taquiri in sample management and data collection is acknowledged. This study was mainly funded by grant number U19 A145431 from National Institutes for Health, ABC, and ITREID from NIH/Fogarty Foundation, USA.",

year = "2003",

month = apr,

day = "15",

doi = "10.1016/S0167-5877(02)00234-9",

language = "English (US)",

volume = "57",

pages = "227--236",

journal = "Preventive Veterinary Medicine",

issn = "0167-5877",

publisher = "Elsevier",

number = "4",

}

TY - JOUR

T1 - Seroincidence of porcine T. solium infection in the Peruvian highlands

AU - Garcia, H. H.

AU - Gonzalez, A. E.

AU - Gavidia, C.

AU - Falcon, N.

AU - Bernal, T.

AU - Verastegui, M.

AU - Rodriguez, S.

AU - Tsang, V. C.W.

AU - Gilman, R. H.

AU - Mayta, H.

AU - Jimenez, J.

AU - Castillo, P.

AU - Evans, C. A.W.

N1 - Funding Information: We are indebted to the people of the Mantaro Valley, who allowed us to do this study. Help from Dr. L.H. Moulton and from M.T. Lopez, C. Guezala, P. Rodriguez, E. Perez, A. Ramirez and C. Taquiri in sample management and data collection is acknowledged. This study was mainly funded by grant number U19 A145431 from National Institutes for Health, ABC, and ITREID from NIH/Fogarty Foundation, USA.

PY - 2003/4/15

Y1 - 2003/4/15

N2 - We performed repeated serological sampling of pigs in an endemic area of the Peruvian highlands (eight villages) to assess the feasibility of detecting incident cases of Taenia solium infection as indicators of ongoing transmission of the parasite. A total of 2245 samples corresponding to 1548 pigs were collected in three sampling rounds (n = 716, 926, and 603, respectively). Village-period specific seroprevalences of antibodies by enzyme-linked immunoelectrotransfer blot (EITB) assay varied from 39% (95% CI: 34, 44) to 76% (95% CI: 72, 79). The prevalence of cysticercosis increased with the age of the pigs (similarly for both sexes). Around 40% of pigs were re-sampled at the end of each 4-month period. Crude incidence risks were 48% (57/120, 95% CI: 43-52) and 58% (111/192, 95% CI: 54-61) for each period. A proportion of seropositive animals became seronegative at the end of each period (23 and 15%). Incidence varied by the village, and the exposure period, and was higher in males than females (but did not differ by age).

AB - We performed repeated serological sampling of pigs in an endemic area of the Peruvian highlands (eight villages) to assess the feasibility of detecting incident cases of Taenia solium infection as indicators of ongoing transmission of the parasite. A total of 2245 samples corresponding to 1548 pigs were collected in three sampling rounds (n = 716, 926, and 603, respectively). Village-period specific seroprevalences of antibodies by enzyme-linked immunoelectrotransfer blot (EITB) assay varied from 39% (95% CI: 34, 44) to 76% (95% CI: 72, 79). The prevalence of cysticercosis increased with the age of the pigs (similarly for both sexes). Around 40% of pigs were re-sampled at the end of each 4-month period. Crude incidence risks were 48% (57/120, 95% CI: 43-52) and 58% (111/192, 95% CI: 54-61) for each period. A proportion of seropositive animals became seronegative at the end of each period (23 and 15%). Incidence varied by the village, and the exposure period, and was higher in males than females (but did not differ by age).

KW - Cysticercosis

KW - EITB

KW - Epidemiology

KW - Incidence

KW - Longitudinal studies

KW - Taenia solium

UR - http://www.scopus.com/inward/record.url?scp=0242586095&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0242586095&partnerID=8YFLogxK

U2 - 10.1016/S0167-5877(02)00234-9

DO - 10.1016/S0167-5877(02)00234-9

M3 - Article

C2 - 12609467

AN - SCOPUS:0242586095

SN - 0167-5877

VL - 57

SP - 227

EP - 236

JO - Preventive Veterinary Medicine

JF - Preventive Veterinary Medicine

IS - 4

ER -

Seroincidence of porcine T. solium infection in the Peruvian highlands

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this