Sequential SPECT and optical imaging of experimental models of prostate cancer with a dual modality inhibitor of the prostate-specific membrane antigen

Sangeeta Ray Banerjee; Mrudula Pullambhatla; Youngjoo Byun; Sridhar Nimmagadda; Catherine A. Foss; Gilbert Green; James J. Fox; Shawn E. Lupold; Ronnie C. Mease; Martin G. Pomper

doi:10.1002/anie.201102872

Sequential SPECT and optical imaging of experimental models of prostate cancer with a dual modality inhibitor of the prostate-specific membrane antigen

Sangeeta Ray Banerjee
, Mrudula Pullambhatla
, Youngjoo Byun
, Sridhar Nimmagadda
, Catherine A. Foss
, Gilbert Green
, James J. Fox
, Shawn E. Lupold
, Ronnie C. Mease
, Martin G. Pomper

School of Medicine

Research output: Contribution to journal › Article › peer-review

79 Scopus citations

Abstract

One reagent for two techniques: Compound [ ¹¹¹In]1 provides a platform for sequential radionuclide and optical imaging of prostate cancer through targeting of the prostate-specific membrane antigen. Because the same subject can be dual-imaged after one injection of the agent, these findings support rapid clinical translation.

Original language	English (US)
Pages (from-to)	9167-9170
Number of pages	4
Journal	Angewandte Chemie - International Edition
Volume	50
Issue number	39
DOIs	https://doi.org/10.1002/anie.201102872
State	Published - Sep 19 2011

Keywords

fluorescent probes
imaging agents
prostate cancer
prostate-specific membrane antigen
radiochemistry

ASJC Scopus subject areas

Catalysis
General Chemistry

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10.1002/anie.201102872

Cite this

Banerjee, S. R., Pullambhatla, M., Byun, Y., Nimmagadda, S., Foss, C. A., Green, G., Fox, J. J., Lupold, S. E., Mease, R. C., & Pomper, M. G. (2011). Sequential SPECT and optical imaging of experimental models of prostate cancer with a dual modality inhibitor of the prostate-specific membrane antigen. Angewandte Chemie - International Edition, 50(39), 9167-9170. https://doi.org/10.1002/anie.201102872

Sequential SPECT and optical imaging of experimental models of prostate cancer with a dual modality inhibitor of the prostate-specific membrane antigen. / Banerjee, Sangeeta Ray; Pullambhatla, Mrudula; Byun, Youngjoo et al.
In: Angewandte Chemie - International Edition, Vol. 50, No. 39, 19.09.2011, p. 9167-9170.

Research output: Contribution to journal › Article › peer-review

Banerjee, SR, Pullambhatla, M, Byun, Y, Nimmagadda, S, Foss, CA, Green, G, Fox, JJ, Lupold, SE, Mease, RC & Pomper, MG 2011, 'Sequential SPECT and optical imaging of experimental models of prostate cancer with a dual modality inhibitor of the prostate-specific membrane antigen', Angewandte Chemie - International Edition, vol. 50, no. 39, pp. 9167-9170. https://doi.org/10.1002/anie.201102872

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Sequential SPECT and optical imaging of experimental models of prostate cancer with a dual modality inhibitor of the prostate-specific membrane antigen

Abstract

Keywords

ASJC Scopus subject areas

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