@article{e67a94d552b547949d8945d338332895,
title = "Sequence of Plasmodium falciparum chromosomes 2, 10, 11 and 14",
abstract = "The mosquito-borne malaria parasite Plasmodium falciparum kills an estimated 0.7-2.7 million people every year, primarily children in sub-Saharan Africa. Without effective interventions, a variety of factors - including the spread of parasites resistant to antimalarial drugs and the increasing insecticide resistance of mosquitoes - may cause the number of malaria cases to double over the next two decades. To stimulate basic research and facilitate the development of new drugs and vaccines, the genome of Plasmodium falciparum clone 3D7 has been sequenced using a chromosome-by-chromosome shotgun strategy. We report here the nucleotide sequences of chromosomes 10, 11 and 14, and a re-analysis of the chromosome 2 sequence. These chromosomes represent about 35% of the 23-megabase P. falciparum genome.",
author = "Gardner, {Malcolm J.} and Shallom, {Shamira J.} and Carlton, {Jane M.} and Salzberg, {Steven L.} and Vishvanath Nene and Azadeh Shoaibi and Anne Ciecko and Jeffery Lynn and Michael Rizzo and Bruce Weaver and Behnam Jarrahi and Michael Brenner and Babak Parvizi and Luke Tallon and Azita Moazzez and David Granger and Claire Fujii and Cheryl Hansen and James Pederson and Tamara Feldblyum and Jeremy Peterson and Bernard Suh and Sam Angiuoli and Mihaela Pertea and Jonathan Allen and Jeremy Selengut and Owen White and Cummings, {Leda M.} and Smith, {Hamilton O.} and Adams, {Mark D.} and Venter, {J. Craig} and Carucci, {Daniel J.} and Hoffman, {Stephen L.} and Fraser, {Claire M.}",
note = "Funding Information: We thank the staff in the computer support and software development groups; J. Thompson and A. Cowman for gifts of YAC clones and for advice; D. Schwartz for optical map data; X. Su for genetic map information; Y. Shaw for help with Fig. 1; M. Harris and M. Ashburner for assistance with the parasite specific GO terms; O. White and M. Gardner for Table 1 and supplementary figures; the other members of the Malaria Genome Sequencing Consortium for discussions; and The Wellcome Trust Plasmodium Genome Mapping Consortium. This work was supported by the Wellcome Trust. Funding Information: We thank our colleagues at The Institute for Genomic Research and the Naval Medical Research Center for support; J. Foster for providing markers for chromosome 14; R. Huestis and K. Fischer for providing RT–PCR data for chromosomes 2 and 3 before publication; and S. Cawley for assistance with phat. This work was supported by the Burroughs Wellcome Fund, the National Institute for Allergy and Infectious Diseases, the Naval Medical Research Center, and the US Army Medical Research and Materiel Command. Copyright: Copyright 2008 Elsevier B.V., All rights reserved.",
year = "2002",
month = oct,
day = "3",
doi = "10.1038/nature01094",
language = "English (US)",
volume = "419",
pages = "531--534",
journal = "Nature",
issn = "0028-0836",
publisher = "Nature Publishing Group",
number = "6906",
}