TY - GEN
T1 - Sensory stimulation enhances functional connectivity towards the somatosensory cortex in upper limb amputation
AU - Ding, Keqin
AU - Dragomir, Andrei
AU - Bose, Rohit
AU - Osborn, Luke
AU - Seet, Manuel
AU - Bezerianos, anastasios
AU - Thakor, Nitish
N1 - Funding Information:
*This work was supported by the SINAPSE startup grant from the National University of Singapore to Nitish Thakor. 1 Department of Biomedical Engineering, Johns Hopkins School of Medicine, Baltimore, MD, USA. [email protected] 2 N.1 Institute for Health, National University of Singapore, Singapore 3 Research & Exploratory Development Department, Johns Hopkins University Applied Physics Laboratory, Laurel, MD, USA 4 Hellenic Institute of Transport, Centre for Research and Technology Hellas, Thessaloniki, Greece 5 Department of Electrical and Computer Engineering, Johns Hopkins University, Baltimore, MD, USA
Publisher Copyright:
© 2021 IEEE.
PY - 2021/5/4
Y1 - 2021/5/4
N2 - Sensory stimulation elicits sensations in the phantom hand of individuals with upper limb amputation. The reinstated sensory information is important to improve phantom limb perception and motor performance. In this work, we aimed to characterize the cortical impact of sensory stimulation on sensorimotor integration in upper limb amputees. To this goal, we investigated dynamic functional connectivity computed from electroencephalogram (EEG) recorded while amputees executed phantom hand movements with and without sensory stimulation. We focused on the dynamic functional connections to the somatosensory system and discovered that non-invasive sensory stimulation induced increased speed of information transfer, shown by decreased temporal distance, and increased number of connections from the motor, somatosensory, and multisensory processing systems. We show that the cortical impact of sensory stimulation is manifested not only through functional activities related to the primary somatosensory system, but also those involving the secondary somatosensory system.
AB - Sensory stimulation elicits sensations in the phantom hand of individuals with upper limb amputation. The reinstated sensory information is important to improve phantom limb perception and motor performance. In this work, we aimed to characterize the cortical impact of sensory stimulation on sensorimotor integration in upper limb amputees. To this goal, we investigated dynamic functional connectivity computed from electroencephalogram (EEG) recorded while amputees executed phantom hand movements with and without sensory stimulation. We focused on the dynamic functional connections to the somatosensory system and discovered that non-invasive sensory stimulation induced increased speed of information transfer, shown by decreased temporal distance, and increased number of connections from the motor, somatosensory, and multisensory processing systems. We show that the cortical impact of sensory stimulation is manifested not only through functional activities related to the primary somatosensory system, but also those involving the secondary somatosensory system.
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U2 - 10.1109/NER49283.2021.9441295
DO - 10.1109/NER49283.2021.9441295
M3 - Conference contribution
AN - SCOPUS:85107500646
T3 - International IEEE/EMBS Conference on Neural Engineering, NER
SP - 226
EP - 229
BT - 2021 10th International IEEE/EMBS Conference on Neural Engineering, NER 2021
PB - IEEE Computer Society
T2 - 10th International IEEE/EMBS Conference on Neural Engineering, NER 2021
Y2 - 4 May 2021 through 6 May 2021
ER -