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Semi-automated Image Segmentation of the Midsystolic Left Ventricular Mitral Valve Complex in Ischemic Mitral Regurgitation

  • Ahmed H. Aly
  • , Abdullah H. Aly
  • , Mahmoud Elrakhawy
  • , Kirlos Haroun
  • , Luis Prieto-Riascos
  • , Robert C. Gorman
  • , Natalie Yushkevich
  • , Yoshiaki Saito
  • , Joseph H. Gorman
  • , Paul A. Yushkevich
  • , Alison M. Pouch

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Ischemic mitral regurgitation (IMR) is primarily a left ventricular disease in which the mitral valve is dysfunctional due to ventricular remodeling after myocardial infarction. Current automated methods have focused on analyzing the mitral valve and left ventricle independently. While these methods have allowed for valuable insights into mechanisms of IMR, they do not fully integrate pathological features of the left ventricle and mitral valve. Thus, there is an unmet need to develop an automated segmentation algorithm for the left ventricular mitral valve complex, in order to allow for a more comprehensive study of this disease. The objective of this study is to generate and evaluate segmentations of the left ventricular mitral valve complex in pre-operative 3D transesophageal echocardiography using multi-atlas label fusion. These patient-specific segmentations could enable future statistical shape analysis for clinical outcome prediction and surgical risk stratification. In this study, we demonstrate a preliminary segmentation pipeline that achieves an average Dice coefficient of 0.78 ± 0.06.

Original languageEnglish (US)
Title of host publicationStatistical Atlases and Computational Models of the Heart. Atrial Segmentation and LV Quantification Challenges - 9th International Workshop, STACOM 2018, Held in Conjunction with MICCAI 2018, Revised Selected Papers
EditorsMihaela Pop, Maxime Sermesant, Jichao Zhao, Shuo Li, Kristin McLeod, Alistair Young, Kawal Rhode, Tommaso Mansi
PublisherSpringer Science and Business Media Deutschland GmbH
Pages142-151
Number of pages10
ISBN (Print)9783030120283
DOIs
StatePublished - 2019
Externally publishedYes
Event9th International Workshop on Statistical Atlases and Computational Models of the Heart: Atrial Segmentation and LV Quantification Challenges, STACOM 2018, held in conjunction with Medical Image Computing and Computer-Assisted Intervention, MICCAI 2018 - Granada, Spain
Duration: Sep 16 2018Sep 16 2018

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume11395 LNCS
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Conference

Conference9th International Workshop on Statistical Atlases and Computational Models of the Heart: Atrial Segmentation and LV Quantification Challenges, STACOM 2018, held in conjunction with Medical Image Computing and Computer-Assisted Intervention, MICCAI 2018
Country/TerritorySpain
CityGranada
Period9/16/189/16/18

Keywords

  • 3D echocardiography
  • Ischemic mitral regurgitation
  • Multi-atlas label fusion

ASJC Scopus subject areas

  • Theoretical Computer Science
  • General Computer Science

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