Self-reported bacterial infections among women with or at risk for human immunodeficiency virus infection

Timothy P. Flanigan, J. W. Hogan, D. Smith, E. Schoenbaum, D. Vlahov, P. Schuman, K. Mayer

    Research output: Contribution to journalArticlepeer-review

    18 Scopus citations


    Bacterial infections are a major cause of morbidity and mortality in persons with human immunodeficiency virus (HIV) infection, particularly women. We performed a cross-sectional analysis of a history of bacterial infections among 1,310 women with or at risk for HIV infection. HIV- seropositive women were significantly more likely than seronegative women to report recent and lifetime histories of bacterial infection, even after history of injection drug use since 1977 was adjusted for; this included recent pneumonia (odds ratio [OR], 3.2; 95% confidence interval [CI], 1.5- 6.6), sinusitis (OR, 1.4; 95% CI, 1.0-2.0), and urinary tract infection (OR, 1.5; 95% CI, 1.1-2.1). Compared with HIV-negative women, women with CD4 cell counts of <200 were about eight times more likely to report recent pneumonia (OR, 7.8; 95% CI, 3.4-17.7); those with CD4 cell counts of 200-500 were almost three times more likely to do so (OR, 2.6; CI, 1.2-5.7). Logistic regression analysis revealed that only CD4 cell category and a recent history of smoking had a significant relationship to self-reported pneumonia.

    Original languageEnglish (US)
    Pages (from-to)608-612
    Number of pages5
    JournalClinical Infectious Diseases
    Issue number3
    StatePublished - 1999

    ASJC Scopus subject areas

    • Microbiology (medical)
    • Infectious Diseases


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