TY - JOUR
T1 - Seizures and epilepsy
T2 - An overview for neuroscientists
AU - Stafstrom, Carl E.
AU - Carmant, Lionel
N1 - Publisher Copyright:
© 2015 Cold Spring Harbor Laboratory Press; all rights reserved.
PY - 2015
Y1 - 2015
N2 - Epilepsy is one of the most common and disabling neurologic conditions, yet we have an incomplete understanding of the detailed pathophysiology and, thus, treatment rationale for much of epilepsy. This article reviews the clinical aspects of seizures and epilepsy with the goal of providing neuroscientists an introduction to aspects that might be amenable to scientific investigation. Seizures and epilepsy are defined, diagnostic methods are reviewed, various clinical syndromes are discussed, and aspects of differential diagnosis, treatment, and prognosis are considered to enable neuroscientists to formulate basic and translational research questions.
AB - Epilepsy is one of the most common and disabling neurologic conditions, yet we have an incomplete understanding of the detailed pathophysiology and, thus, treatment rationale for much of epilepsy. This article reviews the clinical aspects of seizures and epilepsy with the goal of providing neuroscientists an introduction to aspects that might be amenable to scientific investigation. Seizures and epilepsy are defined, diagnostic methods are reviewed, various clinical syndromes are discussed, and aspects of differential diagnosis, treatment, and prognosis are considered to enable neuroscientists to formulate basic and translational research questions.
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U2 - 10.1101/cshperspect.a022426
DO - 10.1101/cshperspect.a022426
M3 - Article
C2 - 26033084
AN - SCOPUS:84936761783
SN - 1943-0264
VL - 7
SP - 1
EP - 19
JO - Cold Spring Harbor Perspectives in Biology
JF - Cold Spring Harbor Perspectives in Biology
IS - 5
ER -