Seizure and mental status change after surgery for pelvic organ prolapse

Hindi E. Stohl, Ralph Daher, Frank Aguirre, Chi Chiung Grace Chen

Research output: Contribution to journalArticlepeer-review


The syndrome of inappropriate antidiuretic hormone secretion (SIADH) is a well-documented postoperative complication but infrequently seen after gynecologic procedures. Clinical presentation is often insidious, and neurologic sequelae may be severe, especially in women. We report the first published case of postoperative hyponatremia due to SIADH after vaginal reconstructive surgery. Our patient sustained a tonic-clonic seizure on postoperative day 2 in the setting of profound hyponatremia. Early detection and prompt treatment allowed her to achieve a complete recovery. Familiarity with uncommon complications of vaginal surgery is important. Prompt initiation of treatment can prevent potentially fatal consequences.

Original languageEnglish (US)
Pages (from-to)1463-1465
Number of pages3
JournalInternational Urogynecology Journal
Issue number11
StatePublished - Nov 2011


  • Hyponatremia
  • Pelvic organ prolapse
  • Seizure

ASJC Scopus subject areas

  • Obstetrics and Gynecology
  • Urology


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