Sedation, analgesia, and neuromuscular paralysis

Research output: Chapter in Book/Report/Conference proceedingChapter


Comfortable patient; ethical and good medical practice. Relieves pain, anxiety, recall; enhances patient safety. Mandated in 2000 by The Joint Commission. Sedation may be particularly difficult to titrate in neurologically compromised patient. Sedatives and analgesics may compromise exam and cerebral physiology. More need for conscious sedation due to recent reduction in pharmacologically induced paralysis in ICU patients. Emphasis on reducing length of ICU stay and cost of hospitalization. Guidelines stress minimizing depth and duration of sedative regimens; overall beneficial for neurologic patient, as more likely to preserve neurologic functions

Original languageEnglish (US)
Title of host publicationHandbook of Neurocritical Care
Subtitle of host publicationSecond Edition
PublisherSpringer New York
Number of pages27
ISBN (Print)9781441968418
StatePublished - Dec 1 2010


  • Adverse reaction
  • Analgesics
  • Depolarizing NMB
  • Hypercarbia
  • Infection
  • Intracranial pathology
  • Metabolic or toxic disarray
  • Nondepolarizing NMB
  • Paralytics
  • Sedatives
  • Succinylcholine

ASJC Scopus subject areas

  • Medicine(all)


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