Twenty-six patients who had a malignant giant-cell tumor of bone - a sarcoma either juxtaposed to a zone of typical benign giant-cell tumor or occurring at the site of a previously documented benign giant-cell tumor - have been seen at the Mayo Clinic. Of the twenty-six tumors, nineteen were secondary to a previous attempt at local control of a benign giant-cell tumor. All but one of these nineteen patients with a secondary tumor had received therapeutic irradiation four to thirty-nine years earlier. The nature and duration of the symptoms and the sites of predilection of the malignant giant-cell tumors were the same as for benign giant-cell tumor. Fibrosarcoma occurred three times as frequently as osteosarcoma. The best results of treatment of the secondary sarcoma were obtained with early ablation.
|Original language||English (US)|
|Number of pages||7|
|Journal||Journal of Bone and Joint Surgery - Series A|
|State||Published - Jan 1 1986|
ASJC Scopus subject areas
- Orthopedics and Sports Medicine