Search for extrapulmonary Pneumocystis carinii in an animal model

H. S. Oz; W. T. Hughes; S. L. Vargas

doi:10.2307/3284183

Search for extrapulmonary Pneumocystis carinii in an animal model

H. S. Oz, W. T. Hughes, S. L. Vargas

School of Medicine

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

Pneumocystis carinii-infected immunosuppressed ferrets and rats were searched for P. carinii cysts and trophozoites in extrapulmonary organs, including the heart, liver, stomach, kidney, and spleen. loci of P. carinii were found in the liver or kidney of 4 (10%) of 40 ferrets but in no extrapulmonary sites of 30 rats with P. carinii pneumonitis. Attempts to identify P. carinii from immunosuppressed rat or ferret blood or propagate the organism intraorbitally in immunosuppressed rats were unsuccessful. Pneumocystis carinii was identified from aspirated stomach contents of ferrets but in none of the rats infected with P. carinii pneumonitis.

Original language	English (US)
Pages (from-to)	357-359
Number of pages	3
Journal	Journal of Parasitology
Volume	82
Issue number	2
DOIs	https://doi.org/10.2307/3284183
State	Published - Apr 1996

ASJC Scopus subject areas

Parasitology
Ecology, Evolution, Behavior and Systematics

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abstract = "Pneumocystis carinii-infected immunosuppressed ferrets and rats were searched for P. carinii cysts and trophozoites in extrapulmonary organs, including the heart, liver, stomach, kidney, and spleen. loci of P. carinii were found in the liver or kidney of 4 (10%) of 40 ferrets but in no extrapulmonary sites of 30 rats with P. carinii pneumonitis. Attempts to identify P. carinii from immunosuppressed rat or ferret blood or propagate the organism intraorbitally in immunosuppressed rats were unsuccessful. Pneumocystis carinii was identified from aspirated stomach contents of ferrets but in none of the rats infected with P. carinii pneumonitis.",

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AB - Pneumocystis carinii-infected immunosuppressed ferrets and rats were searched for P. carinii cysts and trophozoites in extrapulmonary organs, including the heart, liver, stomach, kidney, and spleen. loci of P. carinii were found in the liver or kidney of 4 (10%) of 40 ferrets but in no extrapulmonary sites of 30 rats with P. carinii pneumonitis. Attempts to identify P. carinii from immunosuppressed rat or ferret blood or propagate the organism intraorbitally in immunosuppressed rats were unsuccessful. Pneumocystis carinii was identified from aspirated stomach contents of ferrets but in none of the rats infected with P. carinii pneumonitis.

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Search for extrapulmonary Pneumocystis carinii in an animal model

Abstract

ASJC Scopus subject areas

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