TY - JOUR
T1 - Screening for amblyopia in preverbal children with photoscreening photographs
T2 - II. Sensitivity and specificity of the MTI PhotoScreener
AU - Tong, Patrick Y.
AU - Bassin, Roger E.
AU - Enke-Miyazaki, Erinn
AU - Macke, Jennifer P.
AU - Tielsch, James M.
AU - Stager, David R.
AU - Beauchamp, George R.
AU - Parks, Marshall M.
N1 - Funding Information:
Supported by the National Children’s Eye Care Foundation, Dallas, Texas; the National Institutes of Health (grant no.: 1 K08EY00362-01), Bethesda, Maryland; an unrestricted departmental grant from Research to Prevent Blindness, Inc., New York, New York; the Roy and Niuta Titus Foundation, New York, New York; and the Clinician Scientist Award, Johns Hopkins University, Baltimore, Maryland.
PY - 2000
Y1 - 2000
N2 - Objective: To determine the sensitivity and specificity of vision screening using the Medical Technology and Innovations (MTI), Inc., PhotoScreener. Design: Cross-sectional study. Participants and Testing: Three hundred ninety-two children less than 4 years of age received a complete ophthalmologic examination and were photographed using the MTI PhotoScreener. One hundred three children had normal examinations, and the remaining 284 children had conditions of interest for pediatric screening: ptosis, media opacity, refractive error, or strabismus. Five children were excluded. Main Outcome Measures: The grading of the photographs by the manufacturer's representative was compared with the results of the ophthalmologic examinations. Sensitivity and specificity of vision screening were determined. Results: The analysis of all informative photographs resulted in a sensitivity of 65% and a specificity of 87%. The sensitivity of detection for children with some forms of strabismus was high, up to 95% for esotropia of 10Δ or more. Sensitivities for the detection of ptosis, media opacity, and refractive error were poor in patients where strabismus was not also present. Conclusions: The MTI PhotoScreener may play a role in preverbal vision screening; identification of two of three children with amblyopiogenic factors before age 4 would be an exciting advance in public health. However, improvement in the ability to identify children with media opacity and refractive error is necessary. Improvements may be possible with modifications of the examination failure and photograph grading criteria. (C) 2000 by the American Academy of Ophthalmology.
AB - Objective: To determine the sensitivity and specificity of vision screening using the Medical Technology and Innovations (MTI), Inc., PhotoScreener. Design: Cross-sectional study. Participants and Testing: Three hundred ninety-two children less than 4 years of age received a complete ophthalmologic examination and were photographed using the MTI PhotoScreener. One hundred three children had normal examinations, and the remaining 284 children had conditions of interest for pediatric screening: ptosis, media opacity, refractive error, or strabismus. Five children were excluded. Main Outcome Measures: The grading of the photographs by the manufacturer's representative was compared with the results of the ophthalmologic examinations. Sensitivity and specificity of vision screening were determined. Results: The analysis of all informative photographs resulted in a sensitivity of 65% and a specificity of 87%. The sensitivity of detection for children with some forms of strabismus was high, up to 95% for esotropia of 10Δ or more. Sensitivities for the detection of ptosis, media opacity, and refractive error were poor in patients where strabismus was not also present. Conclusions: The MTI PhotoScreener may play a role in preverbal vision screening; identification of two of three children with amblyopiogenic factors before age 4 would be an exciting advance in public health. However, improvement in the ability to identify children with media opacity and refractive error is necessary. Improvements may be possible with modifications of the examination failure and photograph grading criteria. (C) 2000 by the American Academy of Ophthalmology.
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U2 - 10.1016/S0161-6420(00)00293-1
DO - 10.1016/S0161-6420(00)00293-1
M3 - Article
C2 - 10964818
AN - SCOPUS:0033756551
SN - 0161-6420
VL - 107
SP - 1623
EP - 1629
JO - Ophthalmology
JF - Ophthalmology
IS - 9
ER -