Screening for active tuberculosis: Methodological challenges in implementation and evaluation

Research output: Contribution to journalReview articlepeer-review

24 Scopus citations


As active screening strategies for tuberculosis (TB) continue to rise globally, it has become increasingly important to consider the methodological challenges in d esigning and implementing these strategies. The key challenges associated with TB screening can be summarized in terms of four continua or spectra, namely those of 1) TB disease and diagnostic yield, 2) TB risk and resource availability, 3) TB screening strategies, and 4) outcomes and impact measurements of screening programs. In this review, we provide a discussion of these challenges to help guide development of TB screening strategies that will be effective in a given epidemiological setting.

Original languageEnglish (US)
Pages (from-to)856-865
Number of pages10
JournalInternational Journal of Tuberculosis and Lung Disease
Issue number7
StatePublished - Jul 1 2013


  • Diagnostic techniques and procedures
  • Epidemiology
  • Tuberculosis

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Infectious Diseases


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