Schizophrenia and rheumatoid arthritis: a review

William W. Eaton; Chris Hayward; Ranganathan Ram

doi:10.1016/0920-9964(92)90001-L

Schizophrenia and rheumatoid arthritis: a review

William W. Eaton
, Chris Hayward
, Ranganathan Ram

Research output: Contribution to journal › Review article › peer-review

134 Scopus citations

Abstract

Fourteen epidemiologic studies of the relationship of rheumatoid arthritis to schizophrenia have been conducted between 1934 and 1985. Twelve of the studies report a lower-than-expected rate of rheumatoid arthritis in populations of schizophrenics. Methodologic weaknesses in the studies are assessed. Nutritional, hormonal, psychosocial, genetic, and immunologic data and theories are briefly reviewed which might explain the epidemiologic results. There is sufficient evidence for the negative association between the two disorders to justify further research.

Original language	English (US)
Pages (from-to)	181-192
Number of pages	12
Journal	Schizophrenia Research
Volume	6
Issue number	3
DOIs	https://doi.org/10.1016/0920-9964(92)90001-L
State	Published - Mar 1992
Externally published	Yes

Keywords

(Schizophrenia)
Autoimmune disorder
Epidemiology
Rheumatoid arthritis

ASJC Scopus subject areas

Psychiatry and Mental health
Biological Psychiatry

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10.1016/0920-9964(92)90001-L

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title = "Schizophrenia and rheumatoid arthritis: a review",

abstract = "Fourteen epidemiologic studies of the relationship of rheumatoid arthritis to schizophrenia have been conducted between 1934 and 1985. Twelve of the studies report a lower-than-expected rate of rheumatoid arthritis in populations of schizophrenics. Methodologic weaknesses in the studies are assessed. Nutritional, hormonal, psychosocial, genetic, and immunologic data and theories are briefly reviewed which might explain the epidemiologic results. There is sufficient evidence for the negative association between the two disorders to justify further research.",

keywords = "(Schizophrenia), Autoimmune disorder, Epidemiology, Rheumatoid arthritis",

author = "Eaton, \{William W.\} and Chris Hayward and Ranganathan Ram",

note = "Funding Information: This work was supported in part by NIMH Grant 44653 to W. W. E., Principal Investigator, and NIMH Grant 44801 to Evelyn Bromet, Principal Investigator. The authors would like to thank Jean Lavelle for assistance in typing and editing.",

year = "1992",

month = mar,

doi = "10.1016/0920-9964(92)90001-L",

language = "English (US)",

volume = "6",

pages = "181--192",

journal = "Schizophrenia Research",

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publisher = "Elsevier B.V.",

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}

TY - JOUR

T1 - Schizophrenia and rheumatoid arthritis

T2 - a review

AU - Eaton, William W.

AU - Hayward, Chris

AU - Ram, Ranganathan

N1 - Funding Information: This work was supported in part by NIMH Grant 44653 to W. W. E., Principal Investigator, and NIMH Grant 44801 to Evelyn Bromet, Principal Investigator. The authors would like to thank Jean Lavelle for assistance in typing and editing.

PY - 1992/3

Y1 - 1992/3

N2 - Fourteen epidemiologic studies of the relationship of rheumatoid arthritis to schizophrenia have been conducted between 1934 and 1985. Twelve of the studies report a lower-than-expected rate of rheumatoid arthritis in populations of schizophrenics. Methodologic weaknesses in the studies are assessed. Nutritional, hormonal, psychosocial, genetic, and immunologic data and theories are briefly reviewed which might explain the epidemiologic results. There is sufficient evidence for the negative association between the two disorders to justify further research.

AB - Fourteen epidemiologic studies of the relationship of rheumatoid arthritis to schizophrenia have been conducted between 1934 and 1985. Twelve of the studies report a lower-than-expected rate of rheumatoid arthritis in populations of schizophrenics. Methodologic weaknesses in the studies are assessed. Nutritional, hormonal, psychosocial, genetic, and immunologic data and theories are briefly reviewed which might explain the epidemiologic results. There is sufficient evidence for the negative association between the two disorders to justify further research.

KW - (Schizophrenia)

KW - Autoimmune disorder

KW - Epidemiology

KW - Rheumatoid arthritis

UR - https://www.scopus.com/pages/publications/0026562767

UR - https://www.scopus.com/pages/publications/0026562767#tab=citedBy

U2 - 10.1016/0920-9964(92)90001-L

DO - 10.1016/0920-9964(92)90001-L

M3 - Review article

C2 - 1571312

AN - SCOPUS:0026562767

SN - 0920-9964

VL - 6

SP - 181

EP - 192

JO - Schizophrenia Research

JF - Schizophrenia Research

IS - 3

ER -

Schizophrenia and rheumatoid arthritis: a review

Abstract

Keywords

ASJC Scopus subject areas

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