Schizophrenia and cerebral asymmetry detected by computed tomography

D. J. Luchins, D. R. Weinberger, R. Jed Wyatt

Research output: Contribution to journalArticlepeer-review

51 Scopus citations


The authors nonblindly assessed occipital cerebral asymmetry on computed tomography (CT) scans of 79 schizophrenic or schizoaffective patients and 100 neurological or medical patients. More of the schizophrenic patients had reversals of the normal asymmetry than did controls. The schizophrenics with CT evidence of brain atrophy had a higher frequency of normal asymmetries than did controls, and the schizophrenics without atrophy had more reversed asymmetries. The schizophrenics with reversed asymmetry, compared with those with normal asymmetry, had lower verbal than performance IQ. Comparison of occipital assymetry and lateral ventricular asymmetry indicated that reversed asymmetry in the schizophrenic patients was probably not due to localized atrophy.

Original languageEnglish (US)
Pages (from-to)753-757
Number of pages5
JournalAmerican Journal of Psychiatry
Issue number6
StatePublished - Jan 1 1982
Externally publishedYes

ASJC Scopus subject areas

  • Psychiatry and Mental health


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