TY - GEN
T1 - Scaling exponents of EEG are related to the temporal process of the therapeutic hypothermia following ischemic brain injury
AU - Jiang, Dineng
AU - Wu, Wenqing
AU - Jia, Xiaofeng
AU - Qiu, Yihong
AU - Zhu, Yisheng
AU - Thakor, Nitish
AU - Tong, Shanbao
PY - 2009/1/1
Y1 - 2009/1/1
N2 - Several markers based on quantitative electroencephalogram (qEEG) analysis have been associated with the neuroprotective effects of therapeutic hypothermia on hypoxicischemic encephalopathy (HIE) after cardiac arrest (CA). Nevertheless, the makers by far have not been linked to the temporal process of the ischemic neuronal death. In this study, we investigated the long-range correlations in EEG power in q and a bands before and after CA by detrended fluctuation analysis (DFA). The scaling components by DFA showed that the short-term scaling exponent in α band (i.e. γα 1 ) was well correlated with recovery of brain injury during the latent phase. While the short-term scaling exponent in θ band (i.e. γθ1 ) and the long-term scaling exponent in α band (i.e. γα2) were correlated with the delayed neuronal death after CA. Our preliminary results showed that the long-range correlations in θ and α bands could be related the detail temporal process of therapeutic hypothermia.
AB - Several markers based on quantitative electroencephalogram (qEEG) analysis have been associated with the neuroprotective effects of therapeutic hypothermia on hypoxicischemic encephalopathy (HIE) after cardiac arrest (CA). Nevertheless, the makers by far have not been linked to the temporal process of the ischemic neuronal death. In this study, we investigated the long-range correlations in EEG power in q and a bands before and after CA by detrended fluctuation analysis (DFA). The scaling components by DFA showed that the short-term scaling exponent in α band (i.e. γα 1 ) was well correlated with recovery of brain injury during the latent phase. While the short-term scaling exponent in θ band (i.e. γθ1 ) and the long-term scaling exponent in α band (i.e. γα2) were correlated with the delayed neuronal death after CA. Our preliminary results showed that the long-range correlations in θ and α bands could be related the detail temporal process of therapeutic hypothermia.
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U2 - 10.1109/IEMBS.2009.5334934
DO - 10.1109/IEMBS.2009.5334934
M3 - Conference contribution
C2 - 19965150
AN - SCOPUS:77951015912
SN - 9781424432967
T3 - Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009
SP - 2192
EP - 2195
BT - Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society
PB - IEEE Computer Society
T2 - 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009
Y2 - 2 September 2009 through 6 September 2009
ER -