TY - JOUR
T1 - Saturating the region of the polycystic kidney disease gene with NotI linking clones
AU - Himmelbauer, Heinz
AU - Germino, Greg G.
AU - Ceccherini, Isabella
AU - Romeo, Giovanni
AU - Reeders, Stephen T.
AU - Frischauf, Anna Maria
PY - 1991/2
Y1 - 1991/2
N2 - A NotI-linking library was constructed from a radiation hybrid containing fragments of human chromosome 16. The clones were mapped on a panel of somatic cell hybrids, and 10 different NotI site-containing clones were localized close to and between genetic markers flanking the PKD1 locus. With pulsed-field gel analysis the clones were shown to be distributed over four adjacent ClaI fragments covering 1,200 kb.
AB - A NotI-linking library was constructed from a radiation hybrid containing fragments of human chromosome 16. The clones were mapped on a panel of somatic cell hybrids, and 10 different NotI site-containing clones were localized close to and between genetic markers flanking the PKD1 locus. With pulsed-field gel analysis the clones were shown to be distributed over four adjacent ClaI fragments covering 1,200 kb.
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M3 - Article
C2 - 1990840
AN - SCOPUS:0026023529
SN - 0002-9297
VL - 48
SP - 325
EP - 334
JO - American Journal of Human Genetics
JF - American Journal of Human Genetics
IS - 2
ER -