Abstract
Fine needle aspiration (FNA) is a widely used and well-accepted method for preoperative evaluation of salivary gland lesions. It is a minimally invasive and cost-effective method with high sensitivity and specificity. However, salivary gland FNA presents many challenges due to the increasing number of entities, the heterogeneity of salivary gland lesions and the significant cytomorphologic overlap between many benign and malignant salivary gland neoplasms. Being aware of certain pitfalls and specific problems during the evaluation of salivary gland FNA helps one in avoiding these not-uncommon diagnostic challenges. The major conditions associated with diagnostic pitfalls are 1) matrix-containing lesions; (2) mucinous cysts; (3) Lymphocyte-rich lesions; (4) Basaloid lesions; (5) Oncocytic lesions, and (6) Squamous cells containing lesions. We herein present the major diagnostic pitfalls in salivary gland cytopathology, provide key features for avoiding them and offer helpful advice in achieving accurate diagnoses.
Original language | English (US) |
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Pages (from-to) | 357-369 |
Number of pages | 13 |
Journal | Diagnostic Histopathology |
Volume | 29 |
Issue number | 8 |
DOIs | |
State | Published - Aug 2023 |
Keywords
- Basaloid
- cytology
- diagnostic pitfalls
- fine needle aspiration
- lymphocytes-rich
- matrix
- mucinous cysts
- oncocytes
- salivary gland
- squamous cells
- the milan system for reporting salivary gland cytology
ASJC Scopus subject areas
- Pathology and Forensic Medicine
- Histology