Rotational and translational motion of the heart after myocardial infarction

E. Nagel, M. Stuber, C. Matter, M. Lakatos, P. Boesiger, O. M. Hess

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


The three-dimensional motion of the heart is a combination of radial displacement, rotation, and translation. However, most imaging techniques do not allow accurate assessment of this motion. Myocardial tagging is a new noninvasive technique based on magnetic resonance imaging which permits, labeling of specific myocardial regions and thus allows determination of cardiac rotation, and shortening in different myocardial regions. A systolic 'wringing' and a diastolic 'untwisting' motion can be observed during isovolumic contraction and relaxation in the normal heart. Loss of this systolic wringing motion is found in patients with left ventricular aneurysms, whereas a prolongation of the untwisting with delayed relaxation is seen in the hibernating myocardium. Calcium antagonists improve relaxation and diastolic filling and therefore may be useful in the therapy of ischemic diastolic dysfunction.

Original languageEnglish (US)
Pages (from-to)S31-S35
JournalJournal of cardiovascular pharmacology
Issue numberSUPPL. 2
StatePublished - 1996
Externally publishedYes


  • Calcium antagonist
  • Diastolic function
  • Diastolic untwisting
  • Hibernating myocardium
  • Myocardial infarction
  • Myocardial tagging
  • Systolic wringing

ASJC Scopus subject areas

  • Pharmacology
  • Cardiology and Cardiovascular Medicine


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