Role of transcranial Doppler in optimizing treatment of cerebral vasospasm in subarachnoid hemorrhage

Ribal S. Darwish, Edward Ahn, Nana S. Amiridze

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


This study was undertaken to evaluate the role of transcranial Doppler ultrasonography in arterial blood pressure management during hypervolemia/hypertension/ hemodilution therapy in patients with vasospasm from subarachnoid hemorrhage and correlate this data with neurologic outcome. The study included 18 adult patients, Hunt and Hess grades III-IV. Complete neurologic assessment was performed. Transcranial Doppler indices were calculated by standard formulas. On the basis of our results, resistance area product can be used to estimate the optimal arterial blood pressure in hypervolemia/hypertension/hemodilution therapy. An increase in the cerebral blood flow index was associated with better performance on neurologic examination. Estimated cerebral perfusion pressure from transcranial Doppler data analysis showed poor correlation with cerebral perfusion pressure derived from direct measurement of intracranial pressure in patients with cerebral vasospasm (ρ = 0.15; 95% CI, 0.11-0.39; P =.2590).

Original languageEnglish (US)
Pages (from-to)263-267
Number of pages5
JournalJournal of Intensive Care Medicine
Issue number4
StatePublished - Jul 2008


  • Cerebral blood flow index
  • Cerebral perfusion pressure
  • Cerebral vasospasm
  • Transcranial Doppler ultrasonography
  • Triple-H therapy

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine


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