Role of the cervical lymph nodes as a barrier to metastatic tumor

R. Robinson Baker, Sumner Wood, Pham Van Cong, Soo Tae Kim, Vernon T. Tolo

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


The results of these experiments in rabbi's indicate that 1 × 106 tumor cells are uniformly fatal when injected intravenously. In contrast, the same dose of tumor cells is not necessarily fatal when injected intralymphatically. Arrest within a lymph node occurred in less than 50 per cent of the animals and the ability to contain tumor within the node decreased with time. A radical neck dissection did not significantly reduce the variable barrier effect which was assumed by small regenerated lymphatic vessels and nodes in the dissected side of the neck or by intact nodes in the contralateral side of the neck.

Original languageEnglish (US)
Pages (from-to)654-659
Number of pages6
JournalThe American Journal of Surgery
Issue number5
StatePublished - Nov 1969
Externally publishedYes

ASJC Scopus subject areas

  • Surgery


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