Role of biobanking in urology: a review

Heather J. Chalfin; Elizabeth Fabian; Leslie Mangold; David B. Yeater; Kenneth J. Pienta; Alan W. Partin

doi:10.1111/bju.13606

Role of biobanking in urology: a review

Heather J. Chalfin, Elizabeth Fabian, Leslie Mangold, David B. Yeater, Kenneth J. Pienta, Alan W. Partin

School of Medicine

Research output: Contribution to journal › Review article › peer-review

3 Scopus citations

Abstract

In the current era of individualized medicine, a biorepository of human samples is essential to support clinical and translational research. There have been limited efforts in this arena within the field of urology, as cost, logistical and ethical issues represent significant deterrents to biobanking. The Johns Hopkins Brady Urological Institute Biorepository was founded in 1994 as a resource to facilitate discovery. Since its inception, the biorepository has enabled numerous research endeavours including pivotal trials leading to the regulatory approval of four diagnostic tests for prostate cancer. In the present review, we discuss the current state of biobanking within urology, outline the specific ethical and financial challenges to biobanking as well as solutions, and describe the operations of a successful urological biorepository.

Original language	English (US)
Pages (from-to)	864-868
Number of pages	5
Journal	BJU International
Volume	118
Issue number	6
DOIs	https://doi.org/10.1111/bju.13606
State	Published - Dec 1 2016

Keywords

biobank
biorepository
biospecimen
cost
repository
translational research

ASJC Scopus subject areas

Urology

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10.1111/bju.13606

Cite this

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title = "Role of biobanking in urology: a review",

abstract = "In the current era of individualized medicine, a biorepository of human samples is essential to support clinical and translational research. There have been limited efforts in this arena within the field of urology, as cost, logistical and ethical issues represent significant deterrents to biobanking. The Johns Hopkins Brady Urological Institute Biorepository was founded in 1994 as a resource to facilitate discovery. Since its inception, the biorepository has enabled numerous research endeavours including pivotal trials leading to the regulatory approval of four diagnostic tests for prostate cancer. In the present review, we discuss the current state of biobanking within urology, outline the specific ethical and financial challenges to biobanking as well as solutions, and describe the operations of a successful urological biorepository.",

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AU - Chalfin, Heather J.

AU - Fabian, Elizabeth

AU - Mangold, Leslie

AU - Yeater, David B.

AU - Pienta, Kenneth J.

AU - Partin, Alan W.

PY - 2016/12/1

Y1 - 2016/12/1

N2 - In the current era of individualized medicine, a biorepository of human samples is essential to support clinical and translational research. There have been limited efforts in this arena within the field of urology, as cost, logistical and ethical issues represent significant deterrents to biobanking. The Johns Hopkins Brady Urological Institute Biorepository was founded in 1994 as a resource to facilitate discovery. Since its inception, the biorepository has enabled numerous research endeavours including pivotal trials leading to the regulatory approval of four diagnostic tests for prostate cancer. In the present review, we discuss the current state of biobanking within urology, outline the specific ethical and financial challenges to biobanking as well as solutions, and describe the operations of a successful urological biorepository.

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KW - biospecimen

KW - cost

KW - repository

KW - translational research

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Role of biobanking in urology: a review

Abstract

Keywords

ASJC Scopus subject areas

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