TY - JOUR
T1 - Robbing Host Phosphatidic Acid to Survive
T2 - A Strategy of a Fly Parasite
AU - Coppens, Isabelle
N1 - Funding Information:
The author is grateful to Julia Romano from Johns Hopkins University for her critical reading of the manuscript. The images of the figure have been kindly provided by Dr D. Ferrandon and Adrien Franchet from the Université of Strasbourg, France.
Publisher Copyright:
© 2019 Elsevier Ltd
PY - 2019/5
Y1 - 2019/5
N2 - Drosophila flies can be infected by an obligate fungal intracellular parasite, Tubulinosema ratisbonensis, resulting in a swollen abdomen and often death. Within the fly, the parasite multiplies in the cytoplasm of adipocytes of the fat body, feeds on host lipid droplets, and has a specific requirement for dietary phosphatidic acid.
AB - Drosophila flies can be infected by an obligate fungal intracellular parasite, Tubulinosema ratisbonensis, resulting in a swollen abdomen and often death. Within the fly, the parasite multiplies in the cytoplasm of adipocytes of the fat body, feeds on host lipid droplets, and has a specific requirement for dietary phosphatidic acid.
KW - host phosphatidic acid
KW - intracellular parasitism
KW - microsporidia–Drosophila interaction
KW - nutrient salvage
UR - http://www.scopus.com/inward/record.url?scp=85063366724&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85063366724&partnerID=8YFLogxK
U2 - 10.1016/j.pt.2019.03.006
DO - 10.1016/j.pt.2019.03.006
M3 - Short survey
C2 - 30930263
AN - SCOPUS:85063366724
SN - 1471-4922
VL - 35
SP - 336
EP - 338
JO - Trends in parasitology
JF - Trends in parasitology
IS - 5
ER -