TY - JOUR
T1 - Rnakinetics
T2 - A web server that models secondary structure kinetics of an elongating RNA
AU - Danilova, Ludmila V.
AU - Pervouchine, Dmitri D.
AU - Favorov, Alexander V.
AU - Mironov, Andrei A.
N1 - Funding Information:
This study was partially supported by grants from Howard Hughes Medical Institute (55000309), Ludwig Institute for Cancer Research (CRDF RBO-1268) and RFBR (04-04-49438).
PY - 2006/4
Y1 - 2006/4
N2 - The RNAKinetics server (http://www.ig-msk.ru/RNA/kinetics) is a web interface for the newly developed RNAKinetics software. The software models the dynamics of RNA secondary structure by the means of kinetic analysis of folding transitions of a growing RNA molecule. The result of the modeling is a kinetic ensemble, i.e. a collection of RNA structures that are endowed with probabilities, which depend on time. This approach gives comprehensive probabilistic description of RNA folding pathways, revealing important kinetic details that are not captured by the traditional structure prediction methods. The access to the RNAKinetics server is free.
AB - The RNAKinetics server (http://www.ig-msk.ru/RNA/kinetics) is a web interface for the newly developed RNAKinetics software. The software models the dynamics of RNA secondary structure by the means of kinetic analysis of folding transitions of a growing RNA molecule. The result of the modeling is a kinetic ensemble, i.e. a collection of RNA structures that are endowed with probabilities, which depend on time. This approach gives comprehensive probabilistic description of RNA folding pathways, revealing important kinetic details that are not captured by the traditional structure prediction methods. The access to the RNAKinetics server is free.
KW - Dynamics
KW - Kinetics
KW - RNA folding
KW - RNA secondary structure
UR - http://www.scopus.com/inward/record.url?scp=33745726561&partnerID=8YFLogxK
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U2 - 10.1142/S0219720006001904
DO - 10.1142/S0219720006001904
M3 - Article
C2 - 16819804
AN - SCOPUS:33745726561
SN - 0219-7200
VL - 4
SP - 589
EP - 596
JO - Journal of Bioinformatics and Computational Biology
JF - Journal of Bioinformatics and Computational Biology
IS - 2
ER -