Risk factors for prolonged length of stay in patients undergoing surgery for intramedullary spinal cord tumors

Romaric Waguia; Timothy Y. Wang; Vikram A. Mehta; Luis Ramirez; Edwin McCray; Zach Pennington; Meghan Price; Tara Dalton; César Baëta; Daniel M. Sciubba; Isaac O. Karikari; Muhammad M. Abd-El-Barr; C. Rory Goodwin

doi:10.1016/j.jocn.2021.06.046

Risk factors for prolonged length of stay in patients undergoing surgery for intramedullary spinal cord tumors

Romaric Waguia, Timothy Y. Wang, Vikram A. Mehta, Luis Ramirez, Edwin McCray, Zach Pennington, Meghan Price, Tara Dalton, César Baëta, Daniel M. Sciubba, Isaac O. Karikari, Muhammad M. Abd-El-Barr, C. Rory Goodwin

School of Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

Primary spine tumors are rare neoplasms that affect about 0.62 per 100,000 individuals in the US. Intramedullary spinal cord tumors (IMSCTs) are the rarest of all primary tumors involving the spine and can cause pain, imbalance, urinary dysfunction and neurological deficits. These types of tumors oftentimes necessitate surgical treatment, yet there is a lack of data on hospital length of stay and complication rates following treatment. Given that treatment candidacy, quality of life, and outcomes are tied so closely to potential for prolonged length of stay and postoperative complications, it is important to better understand the factors that increase the risk of these outcomes in patients with IMSCTs. Methods: The National Surgical Quality Improvement Program (NSQIP) database was queried for all patients undergoing surgery for treatment of intramedullary spinal cord tumors between 2005 and 2017. Univariate and multivariate analysis were performed to assess patient risk factors influencing prolonged length of stay and post-op complications. Results: A total of 638 patients were included in the analysis. Pre-operative American Society of Anesthesiology (ASA) physical status classification of 3 and above (OR 1.89; p = 0.0005), dependent functional status (OR 2.76; p = 0.0035) and transfer from facilities other than home (OR 8.12; p <0.0001) were independent predictors of prolonged length of stay (>5 days). The most commonly reported complications were pneumonia (5.7%), urinary tract infection (9.4%), septic shock (3.8%), superficial incisional infection (5.7%), organ or space infection (5.7%), pulmonary embolism (11.3%), DVT requiring therapy (15.1%) and wound dehiscence (5.7%). Conclusion: Our study demonstrated the significant influence of clinical variables on prolonged hospitalization of IMSCT patients. This should be factored into clinical and surgical decision making and when counseling patients of their expected outcomes.

Original language	English (US)
Pages (from-to)	396-401
Number of pages	6
Journal	Journal of Clinical Neuroscience
Volume	91
DOIs	https://doi.org/10.1016/j.jocn.2021.06.046
State	Published - Sep 2021

Keywords

Complications
Length of stay
Spinal tumors

ASJC Scopus subject areas

Clinical Neurology
Neurology
Physiology (medical)
Surgery

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10.1016/j.jocn.2021.06.046

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Waguia, R., Wang, T. Y., Mehta, V. A., Ramirez, L., McCray, E., Pennington, Z., Price, M., Dalton, T., Baëta, C., Sciubba, D. M., Karikari, I. O., Abd-El-Barr, M. M., & Rory Goodwin, C. (2021). Risk factors for prolonged length of stay in patients undergoing surgery for intramedullary spinal cord tumors. Journal of Clinical Neuroscience, 91, 396-401. https://doi.org/10.1016/j.jocn.2021.06.046

Waguia, R, Wang, TY, Mehta, VA, Ramirez, L, McCray, E, Pennington, Z, Price, M, Dalton, T, Baëta, C, Sciubba, DM, Karikari, IO, Abd-El-Barr, MM & Rory Goodwin, C 2021, 'Risk factors for prolonged length of stay in patients undergoing surgery for intramedullary spinal cord tumors', Journal of Clinical Neuroscience, vol. 91, pp. 396-401. https://doi.org/10.1016/j.jocn.2021.06.046

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title = "Risk factors for prolonged length of stay in patients undergoing surgery for intramedullary spinal cord tumors",

abstract = "Primary spine tumors are rare neoplasms that affect about 0.62 per 100,000 individuals in the US. Intramedullary spinal cord tumors (IMSCTs) are the rarest of all primary tumors involving the spine and can cause pain, imbalance, urinary dysfunction and neurological deficits. These types of tumors oftentimes necessitate surgical treatment, yet there is a lack of data on hospital length of stay and complication rates following treatment. Given that treatment candidacy, quality of life, and outcomes are tied so closely to potential for prolonged length of stay and postoperative complications, it is important to better understand the factors that increase the risk of these outcomes in patients with IMSCTs. Methods: The National Surgical Quality Improvement Program (NSQIP) database was queried for all patients undergoing surgery for treatment of intramedullary spinal cord tumors between 2005 and 2017. Univariate and multivariate analysis were performed to assess patient risk factors influencing prolonged length of stay and post-op complications. Results: A total of 638 patients were included in the analysis. Pre-operative American Society of Anesthesiology (ASA) physical status classification of 3 and above (OR 1.89; p = 0.0005), dependent functional status (OR 2.76; p = 0.0035) and transfer from facilities other than home (OR 8.12; p <0.0001) were independent predictors of prolonged length of stay (>5 days). The most commonly reported complications were pneumonia (5.7%), urinary tract infection (9.4%), septic shock (3.8%), superficial incisional infection (5.7%), organ or space infection (5.7%), pulmonary embolism (11.3%), DVT requiring therapy (15.1%) and wound dehiscence (5.7%). Conclusion: Our study demonstrated the significant influence of clinical variables on prolonged hospitalization of IMSCT patients. This should be factored into clinical and surgical decision making and when counseling patients of their expected outcomes.",

keywords = "Complications, Length of stay, Spinal tumors",

author = "Romaric Waguia and Wang, {Timothy Y.} and Mehta, {Vikram A.} and Luis Ramirez and Edwin McCray and Zach Pennington and Meghan Price and Tara Dalton and C{\'e}sar Ba{\"e}ta and Sciubba, {Daniel M.} and Karikari, {Isaac O.} and Abd-El-Barr, {Muhammad M.} and {Rory Goodwin}, C.",

note = "Publisher Copyright: {\textcopyright} 2021",

year = "2021",

month = sep,

doi = "10.1016/j.jocn.2021.06.046",

language = "English (US)",

volume = "91",

pages = "396--401",

journal = "Journal of Clinical Neuroscience",

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T1 - Risk factors for prolonged length of stay in patients undergoing surgery for intramedullary spinal cord tumors

AU - Waguia, Romaric

AU - Wang, Timothy Y.

AU - Mehta, Vikram A.

AU - Ramirez, Luis

AU - McCray, Edwin

AU - Pennington, Zach

AU - Price, Meghan

AU - Dalton, Tara

AU - Baëta, César

AU - Sciubba, Daniel M.

AU - Karikari, Isaac O.

AU - Abd-El-Barr, Muhammad M.

AU - Rory Goodwin, C.

PY - 2021/9

Y1 - 2021/9

N2 - Primary spine tumors are rare neoplasms that affect about 0.62 per 100,000 individuals in the US. Intramedullary spinal cord tumors (IMSCTs) are the rarest of all primary tumors involving the spine and can cause pain, imbalance, urinary dysfunction and neurological deficits. These types of tumors oftentimes necessitate surgical treatment, yet there is a lack of data on hospital length of stay and complication rates following treatment. Given that treatment candidacy, quality of life, and outcomes are tied so closely to potential for prolonged length of stay and postoperative complications, it is important to better understand the factors that increase the risk of these outcomes in patients with IMSCTs. Methods: The National Surgical Quality Improvement Program (NSQIP) database was queried for all patients undergoing surgery for treatment of intramedullary spinal cord tumors between 2005 and 2017. Univariate and multivariate analysis were performed to assess patient risk factors influencing prolonged length of stay and post-op complications. Results: A total of 638 patients were included in the analysis. Pre-operative American Society of Anesthesiology (ASA) physical status classification of 3 and above (OR 1.89; p = 0.0005), dependent functional status (OR 2.76; p = 0.0035) and transfer from facilities other than home (OR 8.12; p <0.0001) were independent predictors of prolonged length of stay (>5 days). The most commonly reported complications were pneumonia (5.7%), urinary tract infection (9.4%), septic shock (3.8%), superficial incisional infection (5.7%), organ or space infection (5.7%), pulmonary embolism (11.3%), DVT requiring therapy (15.1%) and wound dehiscence (5.7%). Conclusion: Our study demonstrated the significant influence of clinical variables on prolonged hospitalization of IMSCT patients. This should be factored into clinical and surgical decision making and when counseling patients of their expected outcomes.

AB - Primary spine tumors are rare neoplasms that affect about 0.62 per 100,000 individuals in the US. Intramedullary spinal cord tumors (IMSCTs) are the rarest of all primary tumors involving the spine and can cause pain, imbalance, urinary dysfunction and neurological deficits. These types of tumors oftentimes necessitate surgical treatment, yet there is a lack of data on hospital length of stay and complication rates following treatment. Given that treatment candidacy, quality of life, and outcomes are tied so closely to potential for prolonged length of stay and postoperative complications, it is important to better understand the factors that increase the risk of these outcomes in patients with IMSCTs. Methods: The National Surgical Quality Improvement Program (NSQIP) database was queried for all patients undergoing surgery for treatment of intramedullary spinal cord tumors between 2005 and 2017. Univariate and multivariate analysis were performed to assess patient risk factors influencing prolonged length of stay and post-op complications. Results: A total of 638 patients were included in the analysis. Pre-operative American Society of Anesthesiology (ASA) physical status classification of 3 and above (OR 1.89; p = 0.0005), dependent functional status (OR 2.76; p = 0.0035) and transfer from facilities other than home (OR 8.12; p <0.0001) were independent predictors of prolonged length of stay (>5 days). The most commonly reported complications were pneumonia (5.7%), urinary tract infection (9.4%), septic shock (3.8%), superficial incisional infection (5.7%), organ or space infection (5.7%), pulmonary embolism (11.3%), DVT requiring therapy (15.1%) and wound dehiscence (5.7%). Conclusion: Our study demonstrated the significant influence of clinical variables on prolonged hospitalization of IMSCT patients. This should be factored into clinical and surgical decision making and when counseling patients of their expected outcomes.

KW - Complications

KW - Length of stay

KW - Spinal tumors

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ER -

Risk factors for prolonged length of stay in patients undergoing surgery for intramedullary spinal cord tumors

Abstract

Keywords

ASJC Scopus subject areas

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