Risk factors for depressive symptomatology in a drug using population

J. C. Buckner, W. Mandell

Research output: Contribution to journalArticlepeer-review

33 Scopus citations


This study employs a prospective design to examine possible personality, drug use, stressful life event, and social support-related variabilities with the onset of a depressive episode in a cohort of psychoactive drug using young adults. Two waves of data, collected one year apart, were available on 942 individuals. Cases (n = 62) were free of depressive symptoms at time 1 but reported significant symptomatology at time 2 as measured by the depression subscale of the Brief Symptom Inventory. Controls (n = 490) were those free of depressive symptoms at both time points. In multivariate analyses, users of the central nervous system depressant methaqualone had a nearly four-fold elevated risk for depressed mood as compared to nonusers. Additional risk factors significant after multivariate adjustment included lower self-esteem at time 1 and negative life events. These results highlight the multifactorial nature of depressive symptomatology.

Original languageEnglish (US)
Pages (from-to)580-585
Number of pages6
JournalAmerican journal of public health
Issue number5
StatePublished - 1990
Externally publishedYes

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health


Dive into the research topics of 'Risk factors for depressive symptomatology in a drug using population'. Together they form a unique fingerprint.

Cite this