Risk factors for central venous catheter-related vascular erosions

L. Mukau, M. A. Talamini, J. V. Sitzmann

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61 Scopus citations


Risk factors for superior vena cava perforations following central venous catheterization for total parenteral nutrition were identified in a retrospective study of 1058 catheters in 853 patients; 540 of these catheters were size 16-gauge (51%) and 518 size 14-gauge (49%). Of the size 14-gauge catheters, 274 (53%) were right-sided and 244 (47%) were left-sided subclavian catheters. Four patients (0.4%) had superior vena cava perforation. All had left-sided large bore 14-gauge catheters. All patients experienced acute symptoms and all had pleural effusions. There was no mortality directly related to vascular erosions. Two risk factors were identified for this complication: (1) catheters originating from the left side (p < 0.05), or (2) large catheters (size 14-gauge or larger) (p < 0.01). We conclude that large bore or left-sided central venous catheter placement represents an increased risk of superior vena cava perforation.

Original languageEnglish (US)
Pages (from-to)513-516
Number of pages4
JournalJournal of Parenteral and Enteral Nutrition
Issue number5
StatePublished - 1991
Externally publishedYes

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Nutrition and Dietetics


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