TY - JOUR
T1 - Right-side endocarditis in injection drug users
T2 - Review of proposed mechanisms of pathogenesis
AU - Frontera, Jennifer A.
AU - Gradon, Jeremy D.
N1 - Copyright:
Copyright 2007 Elsevier B.V., All rights reserved.
PY - 2000
Y1 - 2000
N2 - Infective endocarditis of the right-side heart valves occurs commonly in injection drug users. Although a variety of hypotheses have been put forward to explain this clinical observation, no single hypothesis is adequate. In this article, basic scientific, clinical, and microbiological data on this topic are presented. It is apparent that no clear unifying mechanism emerges to explain the well-documented clinical predilection for the infection of the right-side heart valves in this population. Further investigation of this topic utilizing large international clinical registries may help to clarify matters further.
AB - Infective endocarditis of the right-side heart valves occurs commonly in injection drug users. Although a variety of hypotheses have been put forward to explain this clinical observation, no single hypothesis is adequate. In this article, basic scientific, clinical, and microbiological data on this topic are presented. It is apparent that no clear unifying mechanism emerges to explain the well-documented clinical predilection for the infection of the right-side heart valves in this population. Further investigation of this topic utilizing large international clinical registries may help to clarify matters further.
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U2 - 10.1086/313664
DO - 10.1086/313664
M3 - Review article
C2 - 10671344
AN - SCOPUS:0034017022
SN - 1058-4838
VL - 30
SP - 374
EP - 379
JO - Clinical Infectious Diseases
JF - Clinical Infectious Diseases
IS - 2
ER -