Revealing substrate promiscuity of 1-deoxy-D-xylulose 5-phosphate synthase

Leighanne A. Brammer, Caren Freel Meyers

Research output: Contribution to journalArticlepeer-review

31 Scopus citations


A study of DXP synthase has revealed flexibility In the acceptor substrate binding pocket for nonpolar substrates and has uncovered new details of the catalytic mechanism to show that pyruvate can act as both donor and acceptor substrate.

Original languageEnglish (US)
Pages (from-to)4748-4751
Number of pages4
JournalOrganic Letters
Issue number20
StatePublished - Oct 15 2009

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry


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