Retroperitoneal Paraganglioma: Single-Institution Experience and Review of the Literature

Steven C. Cunningham, Hyun S. Suh, Jordan M. Winter, Elizabeth Montgomery, Richard D. Schulick, John L. Cameron, Charles J. Yeo

Research output: Contribution to journalArticlepeer-review

31 Scopus citations


Paragangliomas are rare tumors arising from extra-adrenal chromaffin cells. We examined the clinical characteristics of all patients at our institution having paragangliomas resected from 1984 through 2005. Of 253 resections, 22 (9%) were retroperitoneal and were selected for further study. The ratio of males to females was 1.3:1, and the median age was 39 years. The average size, rate of metastasis (i.e., malignancy), and rate of function was 7.4 cm, 9.5%, and 57.1%, respectively. Tumors larger than 7 cm were more likely to require adjacent organ resection (P = 0.01). The overall 5-year survival was 73%. Survival was significantly worse after metastasis (P = 0.0023) but did not depend on the tumor diameter, the secreting function of the tumor, the status of surgical margins of resection, or status of the resected lymph nodes.

Original languageEnglish (US)
Pages (from-to)1156-1163
Number of pages8
JournalJournal of Gastrointestinal Surgery
Issue number8
StatePublished - Sep 2006


  • Retroperitoneal
  • paraganglioma
  • surgery
  • survival

ASJC Scopus subject areas

  • Surgery
  • Gastroenterology


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