Retinal disease in marfan syndrome: From the marfan eye consortium of Chicago

Safa Rahmani, Alice T. Lyon, Amani A. Fawzi, Irene H. Maumenee, Marilyn B. Mets

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Background and Objective: To study the prevalence of peripheral retinal disease in patients with Marfan Syndrome (MFS). Patients and Methods: In this observational, cross-sectional case series, patients with MFS were recruited by the Marfan Eye Consortium of Chicago during the National Marfan Foundation's annual conference. Patients underwent a fully dilated exam by vitreoretinal specialists in addition to ultra- widefield fundus photography using a scanning laser ophthalmoscope (Optos 200Tx; Optos PLC, Dunfermline, Scotland, United Kingdom). Results: Clinical examination revealed posterior segment pathology in 18% of eyes with increased incidence to 70% in patients with a subluxed lens. In six out of 10 subjects in whom the clinical exam was suboptimal (young age, small pupil, and limited cooperation), the Optos provided a superior view of the peripheral retina compared to clinical exam alone. Conclusion: Clinical exam of MFS patients revealed similar posterior segment pathology as noted in previous literature, with improved detection of peripheral retinal disease with the use of ultra-widefield imaging.

Original languageEnglish (US)
Pages (from-to)936-941
Number of pages6
JournalOphthalmic Surgery Lasers and Imaging Retina
Issue number9
StatePublished - Oct 2015

ASJC Scopus subject areas

  • Surgery
  • Ophthalmology


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