Retention of calcium oxalate crystals in renal tubules

S. R. Khan, R. L. Hackett

Research output: Contribution to journalArticlepeer-review

66 Scopus citations


Crystal retention within the renal tubules is essential for nephrolithiasis and the development of urinary stone disease. We studied the mechanisms involved in this process by inducing calcium oxalate crystal deposition within the rat renal tubules and examining them using various microscopic techniques. Crystals appeared to be retained either by attachment to the tubular epithelium or by aggregating with other crystals thus becoming large enough to be retained by their collective size.

Original languageEnglish (US)
Pages (from-to)707-712
Number of pages6
JournalScanning Microscopy
Issue number3
StatePublished - Sep 1991
Externally publishedYes

ASJC Scopus subject areas

  • Instrumentation


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