Restoring blood pressure reperfused Wernicke's area and improved language

Argye E. Hillis, P. B. Barker, N. J. Beauchamp, B. D. Winters, M. Mirski, R. J. Wityk

Research output: Contribution to journalArticlepeer-review

79 Scopus citations


Longitudinal clinical and imaging data from a patient who sustained a left frontal-temporal stroke with hypoperfusion of the adjacent Wernicke's area are reported. His language deficits were partially ameliorated by pharmacologically increasing his blood pressure, and were exacerbated when blood pressure dropped. There was a striking temporal and statistical correlation between mean arterial pressure and language accuracy. MR perfusion imaging showed that language gains were accompanied by improved perfusion of Wernicke's area when mean arterial pressure was increased.

Original languageEnglish (US)
Pages (from-to)670-672
Number of pages3
Issue number5
StatePublished - Mar 13 2001

ASJC Scopus subject areas

  • Clinical Neurology


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