Restenosis after coronary balloon angioplasty

Richard A. Lange, Eduardo D. Flores, L. David Hillis

Research output: Contribution to journalArticlepeer-review

12 Scopus citations


A recurrence of stenosis (restenosis) following successful coronary angioplasty continues to be a frequent problem limiting the long-term efficacy of the procedure. An overexuberant reparative response to the arterial injury induced by balloon dilatation leads to intimal hyperplasia, the major mechanism responsible for restenosis. Although none has yet been proven effective, agents designed to prevent this hyperplastic response are under investigation.

Original languageEnglish (US)
Pages (from-to)127-132
Number of pages6
JournalAnnual Review of Medicine
StatePublished - 1991
Externally publishedYes


  • Intimal hyperplasia
  • PTCA

ASJC Scopus subject areas

  • Cell Biology
  • Medicine(all)


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