Respiration induced fiducial motion tracking in ultrasound using an extended SFA approach

Kunlin Cao, Bryan Bednarz, L. S. Smith, Thomas K F Foo, Kedar A. Patwardhan

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations


Radiation therapy (RT) plays an essential role in the management of cancers. The precision of the treatment delivery process in chest and abdominal cancers is often impeded by respiration induced tumor positional variations, which are accounted for by using larger therapeutic margins around the tumor volume leading to sub-optimal treatment deliveries and risk to healthy tissue. Real-time tracking of tumor motion during RT will help reduce unnecessary margin area and benefit cancer patients by allowing the treatment volume to closely match the positional variation of the tumor volume over time. In this work, we propose a fast approach which enables transferring the pre-estimated target (e.g. tumor) motion extracted from ultrasound (US) image sequences in training stage (e.g. before RT) to online data in real-time (e.g. acquired during RT). The method is based on extracting feature points of the target object, exploiting low-dimensional description of the feature motion through slow feature analysis, and finding the most similar image frame from training data for estimating current/online object location. The approach is evaluated on two 2D + time and one 3D + time US acquisitions. The locations of six annotated fiducials are used for designing experiments and validating tracking accuracy. The average fiducial distance between expert's annotation and the location extracted from our indexed training frame is 1.9±0.5mm. Adding a fast template matching procedure within a small search range reduces the distance to 1.4±0.4mm. The tracking time per frame is on the order of millisecond, which is below the frame acquisition time.

Original languageEnglish (US)
Title of host publicationMedical Imaging 2015: Ultrasonic Imaging and Tomography
ISBN (Print)9781628415094
StatePublished - 2015
Externally publishedYes
EventMedical Imaging 2015: Ultrasonic Imaging and Tomography - Orlando, United States
Duration: Feb 22 2015Feb 23 2015


OtherMedical Imaging 2015: Ultrasonic Imaging and Tomography
Country/TerritoryUnited States


  • Feature Extraction
  • Slow Feature Analysis
  • Template Matching
  • Ultrasound

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Radiology Nuclear Medicine and imaging


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