Reprogram to pluripotency: A new logic and a chemical cocktail

Hongjun Song; Guo Li Ming

doi:10.1093/nsr/nwt007

Reprogram to pluripotency: A new logic and a chemical cocktail

Hongjun Song, Guo Li Ming

School of Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

Somatic cells from animals and humans can be reprogrammed into pluripotent stem cells by pluripotency factors. Hongkui Deng and colleagues discovered that pluripotency can also be induced with exogenous lineage specifiers via balancing competing differentiation forces. In a related study they achieved, for the first time, restoration of pluripotency in adult somatic cells using a chemical cocktail alone.

Original language	English (US)
Pages (from-to)	6-7
Number of pages	2
Journal	National Science Review
Volume	1
Issue number	1
DOIs	https://doi.org/10.1093/nsr/nwt007
State	Published - 2014

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title = "Reprogram to pluripotency: A new logic and a chemical cocktail",

abstract = "Somatic cells from animals and humans can be reprogrammed into pluripotent stem cells by pluripotency factors. Hongkui Deng and colleagues discovered that pluripotency can also be induced with exogenous lineage specifiers via balancing competing differentiation forces. In a related study they achieved, for the first time, restoration of pluripotency in adult somatic cells using a chemical cocktail alone.",

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AB - Somatic cells from animals and humans can be reprogrammed into pluripotent stem cells by pluripotency factors. Hongkui Deng and colleagues discovered that pluripotency can also be induced with exogenous lineage specifiers via balancing competing differentiation forces. In a related study they achieved, for the first time, restoration of pluripotency in adult somatic cells using a chemical cocktail alone.

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Reprogram to pluripotency: A new logic and a chemical cocktail

Abstract

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