Replication of the RNA genome

J. T. August, Lillian Eoyang, M. T.Franze De Fernandez, S. Hasegawa, C. H. Kuo, U. Rensing, Lucille Shapiro

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Several steps in the synthesis in vitro of infectious bacteriophage RNA can now be described. The reaction catalyzed by the Qβ RNA polymerase is known to involve several components, including the enzyme, host cell factors, Qβ RNA template, and the strand complementary to the Qβ RNA. The interaction of these components and the mechanims of the reaction appears to be considerably more complex than was proposed in earlier models.

Original languageEnglish (US)
Pages (from-to)187-195
Number of pages9
JournalJournal of Cellular Physiology
Issue number1 S
StatePublished - Oct 1969

ASJC Scopus subject areas

  • Physiology
  • Clinical Biochemistry
  • Cell Biology


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