Repair of articular cartilage and meniscal tears by photoactive dyes: in-vivo study

Millard M. Judy; Robert W M D Jackson; Hany R M D Nosir; James Lester Matthews; David E. Lewis; Ronald E. Utecht; Dongwu Yuan

Repair of articular cartilage and meniscal tears by photoactive dyes: in-vivo study

Millard M. Judy, Robert W M D Jackson, Hany R M D Nosir, James Lester Matthews, David E. Lewis, Ronald E. Utecht, Dongwu Yuan

Research output: Chapter in Book/Report/Conference proceeding › Chapter

6 Scopus citations

Abstract

We describe healing results of our 6 month study of a repair procedure which evokes the healing response in meniscal tears and partial thickness defects in articular cartilage by a non-thermal tissue sparing photochemical weld using 1,8-naphthalimide dyes. Welds of incisional flaps in adult sheep meniscus and femoral articular cartilage were made using the dye MBM Gold 012011012 at 12 mM in PBS, 457.9nm Argon ion laser radiation at 800 mW/cm ², 7.5 minutes with approximately 1 kg/cm ² externally applied pressure. Gross appearance of tissues in all welded knees appeared normal. Hematoxylin and eosin stained sections disclosed close bonding of welded areas and continuing healing response as cellular recruitment.

Original language	English (US)
Title of host publication	Proceedings of SPIE - The International Society for Optical Engineering
Editors	Frederic Laffitte, Raimund Hibst, Hans-Dieter Reidenbach, Herbert J. Geschwind, Giulio Maira, et.al.
Pages	436-440
Number of pages	5
Volume	2922
State	Published - 1996
Externally published	Yes
Event	Laser Applications in Medicine and Dentistry - Vienna, Austria Duration: Sep 7 1996 → Sep 10 1996

Other

Other	Laser Applications in Medicine and Dentistry
City	Vienna, Austria
Period	9/7/96 → 9/10/96

ASJC Scopus subject areas

Engineering(all)

Cite this

Judy, M. M., Jackson, R. W. M. D., Nosir, H. R. M. D., Matthews, J. L., Lewis, D. E., Utecht, R. E., & Yuan, D. (1996). Repair of articular cartilage and meniscal tears by photoactive dyes: in-vivo study. In F. Laffitte, R. Hibst, H-D. Reidenbach, H. J. Geschwind, G. Maira, & et.al. (Eds.), Proceedings of SPIE - The International Society for Optical Engineering (Vol. 2922, pp. 436-440)

Repair of articular cartilage and meniscal tears by photoactive dyes : in-vivo study. / Judy, Millard M.; Jackson, Robert W M D; Nosir, Hany R M D et al.

Proceedings of SPIE - The International Society for Optical Engineering. ed. / Frederic Laffitte; Raimund Hibst; Hans-Dieter Reidenbach; Herbert J. Geschwind; Giulio Maira; et.al. Vol. 2922 1996. p. 436-440.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Judy, MM, Jackson, RWMD, Nosir, HRMD, Matthews, JL, Lewis, DE, Utecht, RE & Yuan, D 1996, Repair of articular cartilage and meniscal tears by photoactive dyes: in-vivo study. in F Laffitte, R Hibst, H-D Reidenbach, HJ Geschwind, G Maira & et.al. (eds), Proceedings of SPIE - The International Society for Optical Engineering. vol. 2922, pp. 436-440, Laser Applications in Medicine and Dentistry, Vienna, Austria, 9/7/96.

Judy, Millard M. ; Jackson, Robert W M D ; Nosir, Hany R M D et al. / Repair of articular cartilage and meniscal tears by photoactive dyes : in-vivo study. Proceedings of SPIE - The International Society for Optical Engineering. editor / Frederic Laffitte ; Raimund Hibst ; Hans-Dieter Reidenbach ; Herbert J. Geschwind ; Giulio Maira ; et.al. Vol. 2922 1996. pp. 436-440

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abstract = "We describe healing results of our 6 month study of a repair procedure which evokes the healing response in meniscal tears and partial thickness defects in articular cartilage by a non-thermal tissue sparing photochemical weld using 1,8-naphthalimide dyes. Welds of incisional flaps in adult sheep meniscus and femoral articular cartilage were made using the dye MBM Gold 012011012 at 12 mM in PBS, 457.9nm Argon ion laser radiation at 800 mW/cm 2, 7.5 minutes with approximately 1 kg/cm 2 externally applied pressure. Gross appearance of tissues in all welded knees appeared normal. Hematoxylin and eosin stained sections disclosed close bonding of welded areas and continuing healing response as cellular recruitment.",

author = "Judy, {Millard M.} and Jackson, {Robert W M D} and Nosir, {Hany R M D} and Matthews, {James Lester} and Lewis, {David E.} and Utecht, {Ronald E.} and Dongwu Yuan",

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AB - We describe healing results of our 6 month study of a repair procedure which evokes the healing response in meniscal tears and partial thickness defects in articular cartilage by a non-thermal tissue sparing photochemical weld using 1,8-naphthalimide dyes. Welds of incisional flaps in adult sheep meniscus and femoral articular cartilage were made using the dye MBM Gold 012011012 at 12 mM in PBS, 457.9nm Argon ion laser radiation at 800 mW/cm 2, 7.5 minutes with approximately 1 kg/cm 2 externally applied pressure. Gross appearance of tissues in all welded knees appeared normal. Hematoxylin and eosin stained sections disclosed close bonding of welded areas and continuing healing response as cellular recruitment.

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ER -

Repair of articular cartilage and meniscal tears by photoactive dyes: in-vivo study

Abstract

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ASJC Scopus subject areas

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