TY - JOUR
T1 - Renal cell carcinoma
T2 - Resection of solitary and multiple metastases
AU - Pogrebniak, Helen W.
AU - Haas, Gabe
AU - Linehan, W. Marston
AU - Rosenberg, Steven A.
AU - Pass, Harvey I.
N1 - Copyright:
Copyright 2018 Elsevier B.V., All rights reserved.
PY - 1992/7
Y1 - 1992/7
N2 - Between 1985 and 1991, 23 patients underwent resection of pulmonary metastases from renal cell carcinoma, of whom 18 had previously received interleukin-2 based immunotherapies. Mean survival from exploration in all patients was 43 months. Survival after resection did not correlate with the number of nodules on preoperative tomograms, the number of nodules resected, or the disease-free interval. Patients who underwent complete resection of metastatic disease (n = 15), however, had a significantly longer survival (mean, 49 months; median not yet achieved) compared with patients with incomplete resection (median, 16 months) (p2 = 0.02). Two of the 15 patients who underwent curative resections are presently free of disease greater than 45 months after exploration. These data support surgical resection of isolated pulmonary metastatic disease from renal cell cancer.
AB - Between 1985 and 1991, 23 patients underwent resection of pulmonary metastases from renal cell carcinoma, of whom 18 had previously received interleukin-2 based immunotherapies. Mean survival from exploration in all patients was 43 months. Survival after resection did not correlate with the number of nodules on preoperative tomograms, the number of nodules resected, or the disease-free interval. Patients who underwent complete resection of metastatic disease (n = 15), however, had a significantly longer survival (mean, 49 months; median not yet achieved) compared with patients with incomplete resection (median, 16 months) (p2 = 0.02). Two of the 15 patients who underwent curative resections are presently free of disease greater than 45 months after exploration. These data support surgical resection of isolated pulmonary metastatic disease from renal cell cancer.
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U2 - 10.1016/0003-4975(92)91136-W
DO - 10.1016/0003-4975(92)91136-W
M3 - Article
C2 - 1610251
AN - SCOPUS:0026663622
SN - 0003-4975
VL - 54
SP - 33
EP - 38
JO - The Annals of thoracic surgery
JF - The Annals of thoracic surgery
IS - 1
ER -