Relationship between sporadic hyperplastic polyps and colorectal neoplasia in hispanic veterans

Rafael Pérez, Arnaldo Lasa, Doris H. Toro, Marcia Cruz-Correa, Jaime Martínez-Souss

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Objective: Hyperplastic polyps (HP) traditionally have been regarded as having no malignant potential. Some studies have suggested that HP in the distal colon may predict presence of adenomatous polyps in the proximal colon. Other studies have failed to show this relationship. The purpose of this study was to evaluate for the first time in our Hispanic veterans population if there was a relationship between the presence of sporadic HP and colorectal neoplasia (CRN) and to evaluate if proposed risk factors for CRN are also risk factors for sporadic HP. Methods: The study consisted of a retrospective review of all the medical records of patients who underwent a colonoscopy for the first time during the calendar year 2005 and had a pathologic diagnosis of HP, tubular adenoma (TA), tubulovillous adenoma (TVA), villous adenoma (VA) and/or colon adenocarcinoma at the VA Caribbean Healthcare System. Patient's age, BMI, smoking and alcohol use history, presence of DM, cholesterol and triglyceride levels, use of aspirin and the size and location of the lesions were recorded. Records with incomplete data and patients with a prior colonoscopy were excluded. Results: 861 patient records were reviewed of which 405 met the inclusion criteria. Most patients (99%) of the patients were males, mean age 67.5 (range 36-87). The total number of colonic lesions was 1,065 (240 hyperplastic, 825 CRN). Histologic evaluation of lesions revealed: 121 patients who had HP, 331 with TA, 33 with TVA, 12 with VA, 13 with serrated adenomas and 61 patients had adenocarcinoma. Univariate analysis revealed that patients with HP appeared to have a lower likelihood of having TA (p

Original languageEnglish (US)
Pages (from-to)372-376
Number of pages5
JournalPuerto Rico Health Sciences Journal
Issue number4
StatePublished - 2010
Externally publishedYes


  • Adenocarcinoma
  • Neoplasia
  • Polyps

ASJC Scopus subject areas

  • Medicine(all)


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