Regression of metastatic renal cell carcinoma after cytoreductive nephrectomy

S. G. Marcus, P. L. Choyke, R. Reiter, G. S. Jaffe, R. B. Alexander, W. M. Linehan, S. A. Rosenberg, M. M. Walther, A. C. Novick, F. F. Marshall

Research output: Contribution to journalArticlepeer-review

108 Scopus citations


Fewer than 1% of patients with renal cell carcinoma are reported to experience spontaneous regression of metastatic lesions after nephrectomy. We report on 4 of 91 patients (4.4%) with metastatic renal cell carcinoma who had spontaneous regression of all metastatic lesions after cytoreductive nephrectomy. These patients were carefully selected before surgery for the ability to receive high dose interleukin-2. One patient had recurrence at 2 months, 1 had recurrence at 11 months, and 2 had no evidence of disease at 3 and 4.5 years.

Original languageEnglish (US)
Pages (from-to)463-466
Number of pages4
JournalJournal of Urology
Issue number2
StatePublished - 1993
Externally publishedYes


  • carcinoma, renal cell
  • kidney
  • neoplasm metastasis
  • neoplasm regression, spontaneous
  • nephrectomy

ASJC Scopus subject areas

  • Urology


Dive into the research topics of 'Regression of metastatic renal cell carcinoma after cytoreductive nephrectomy'. Together they form a unique fingerprint.

Cite this