Regression of metastatic renal cell carcinoma after cytoreductive nephrectomy

S. G. Marcus; P. L. Choyke; R. Reiter; G. S. Jaffe; R. B. Alexander; W. M. Linehan; S. A. Rosenberg; M. M. Walther; A. C. Novick; F. F. Marshall

doi:10.1016/S0022-5347(17)35514-3

Regression of metastatic renal cell carcinoma after cytoreductive nephrectomy

S. G. Marcus, P. L. Choyke, R. Reiter, G. S. Jaffe, R. B. Alexander, W. M. Linehan, S. A. Rosenberg, M. M. Walther, A. C. Novick, F. F. Marshall

Research output: Contribution to journal › Article › peer-review

108 Scopus citations

Abstract

Fewer than 1% of patients with renal cell carcinoma are reported to experience spontaneous regression of metastatic lesions after nephrectomy. We report on 4 of 91 patients (4.4%) with metastatic renal cell carcinoma who had spontaneous regression of all metastatic lesions after cytoreductive nephrectomy. These patients were carefully selected before surgery for the ability to receive high dose interleukin-2. One patient had recurrence at 2 months, 1 had recurrence at 11 months, and 2 had no evidence of disease at 3 and 4.5 years.

Original language	English (US)
Pages (from-to)	463-466
Number of pages	4
Journal	Journal of Urology
Volume	150
Issue number	2
DOIs	https://doi.org/10.1016/S0022-5347(17)35514-3
State	Published - 1993
Externally published	Yes

Keywords

carcinoma, renal cell
kidney
neoplasm metastasis
neoplasm regression, spontaneous
nephrectomy

ASJC Scopus subject areas

Urology

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10.1016/S0022-5347(17)35514-3

Cite this

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title = "Regression of metastatic renal cell carcinoma after cytoreductive nephrectomy",

abstract = "Fewer than 1% of patients with renal cell carcinoma are reported to experience spontaneous regression of metastatic lesions after nephrectomy. We report on 4 of 91 patients (4.4%) with metastatic renal cell carcinoma who had spontaneous regression of all metastatic lesions after cytoreductive nephrectomy. These patients were carefully selected before surgery for the ability to receive high dose interleukin-2. One patient had recurrence at 2 months, 1 had recurrence at 11 months, and 2 had no evidence of disease at 3 and 4.5 years.",

keywords = "carcinoma, renal cell, kidney, neoplasm metastasis, neoplasm regression, spontaneous, nephrectomy",

author = "Marcus, {S. G.} and Choyke, {P. L.} and R. Reiter and Jaffe, {G. S.} and Alexander, {R. B.} and Linehan, {W. M.} and Rosenberg, {S. A.} and Walther, {M. M.} and Novick, {A. C.} and Marshall, {F. F.}",

year = "1993",

doi = "10.1016/S0022-5347(17)35514-3",

language = "English (US)",

volume = "150",

pages = "463--466",

journal = "Journal of Urology",

issn = "0022-5347",

publisher = "Elsevier Inc.",

number = "2",

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TY - JOUR

T1 - Regression of metastatic renal cell carcinoma after cytoreductive nephrectomy

AU - Marcus, S. G.

AU - Choyke, P. L.

AU - Reiter, R.

AU - Jaffe, G. S.

AU - Alexander, R. B.

AU - Linehan, W. M.

AU - Rosenberg, S. A.

AU - Walther, M. M.

AU - Novick, A. C.

AU - Marshall, F. F.

PY - 1993

Y1 - 1993

N2 - Fewer than 1% of patients with renal cell carcinoma are reported to experience spontaneous regression of metastatic lesions after nephrectomy. We report on 4 of 91 patients (4.4%) with metastatic renal cell carcinoma who had spontaneous regression of all metastatic lesions after cytoreductive nephrectomy. These patients were carefully selected before surgery for the ability to receive high dose interleukin-2. One patient had recurrence at 2 months, 1 had recurrence at 11 months, and 2 had no evidence of disease at 3 and 4.5 years.

AB - Fewer than 1% of patients with renal cell carcinoma are reported to experience spontaneous regression of metastatic lesions after nephrectomy. We report on 4 of 91 patients (4.4%) with metastatic renal cell carcinoma who had spontaneous regression of all metastatic lesions after cytoreductive nephrectomy. These patients were carefully selected before surgery for the ability to receive high dose interleukin-2. One patient had recurrence at 2 months, 1 had recurrence at 11 months, and 2 had no evidence of disease at 3 and 4.5 years.

KW - carcinoma, renal cell

KW - kidney

KW - neoplasm metastasis

KW - neoplasm regression, spontaneous

KW - nephrectomy

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SN - 0022-5347

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EP - 466

JO - Journal of Urology

JF - Journal of Urology

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ER -

Regression of metastatic renal cell carcinoma after cytoreductive nephrectomy

Abstract

Keywords

ASJC Scopus subject areas

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