Regional heterogeneity of choline acetyltransferase activity in primate neocortex

John Lehmann, Robert G. Struble, Piero G. Antuono, Joseph T. Coyle, Linda C. Cork, Donald L. Price

Research output: Contribution to journalArticlepeer-review

42 Scopus citations


Choline acetyltransferase activity in precentral and temporal regions of primate neocortex is 2.5-fold higher than in occipital cortex. These results suggest large differences in the density of innervation in different regions of primate neocortex by the nucleus basalis of Meynert.

Original languageEnglish (US)
Pages (from-to)361-364
Number of pages4
JournalBrain research
Issue number2
StatePublished - Nov 26 1984


  • Alzheimer's disease
  • acetylcholine
  • choline acetyltransferase
  • cortex
  • glutamic acid decarboxylase
  • nucleus basalis of Meynert

ASJC Scopus subject areas

  • Neuroscience(all)
  • Molecular Biology
  • Clinical Neurology
  • Developmental Biology


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