Regional heterogeneity of choline acetyltransferase activity in primate neocortex

John Lehmann; Robert G. Struble; Piero G. Antuono; Joseph T. Coyle; Linda C. Cork; Donald L. Price

doi:10.1016/0006-8993(84)90134-3

Regional heterogeneity of choline acetyltransferase activity in primate neocortex

John Lehmann, Robert G. Struble, Piero G. Antuono, Joseph T. Coyle, Linda C. Cork, Donald L. Price

School of Medicine

Research output: Contribution to journal › Article › peer-review

42 Scopus citations

Abstract

Choline acetyltransferase activity in precentral and temporal regions of primate neocortex is 2.5-fold higher than in occipital cortex. These results suggest large differences in the density of innervation in different regions of primate neocortex by the nucleus basalis of Meynert.

Original language	English (US)
Pages (from-to)	361-364
Number of pages	4
Journal	Brain research
Volume	322
Issue number	2
DOIs	https://doi.org/10.1016/0006-8993(84)90134-3
State	Published - Nov 26 1984

Keywords

Alzheimer's disease
acetylcholine
choline acetyltransferase
cortex
glutamic acid decarboxylase
nucleus basalis of Meynert

ASJC Scopus subject areas

Neuroscience(all)
Molecular Biology
Clinical Neurology
Developmental Biology

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10.1016/0006-8993(84)90134-3

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abstract = "Choline acetyltransferase activity in precentral and temporal regions of primate neocortex is 2.5-fold higher than in occipital cortex. These results suggest large differences in the density of innervation in different regions of primate neocortex by the nucleus basalis of Meynert.",

keywords = "Alzheimer's disease, acetylcholine, choline acetyltransferase, cortex, glutamic acid decarboxylase, nucleus basalis of Meynert",

author = "John Lehmann and Struble, {Robert G.} and Antuono, {Piero G.} and Coyle, {Joseph T.} and Cork, {Linda C.} and Price, {Donald L.}",

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AU - Lehmann, John

AU - Struble, Robert G.

AU - Antuono, Piero G.

AU - Coyle, Joseph T.

AU - Cork, Linda C.

AU - Price, Donald L.

PY - 1984/11/26

Y1 - 1984/11/26

N2 - Choline acetyltransferase activity in precentral and temporal regions of primate neocortex is 2.5-fold higher than in occipital cortex. These results suggest large differences in the density of innervation in different regions of primate neocortex by the nucleus basalis of Meynert.

AB - Choline acetyltransferase activity in precentral and temporal regions of primate neocortex is 2.5-fold higher than in occipital cortex. These results suggest large differences in the density of innervation in different regions of primate neocortex by the nucleus basalis of Meynert.

KW - Alzheimer's disease

KW - acetylcholine

KW - choline acetyltransferase

KW - cortex

KW - glutamic acid decarboxylase

KW - nucleus basalis of Meynert

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ER -

Regional heterogeneity of choline acetyltransferase activity in primate neocortex

Abstract

Keywords

ASJC Scopus subject areas

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